Self-administration of the high-affinity cocaine analog 2β-carbomethoxy--(4-fluorophenyl) tropane

RD Spealman, J Bergman, BK Madras - Pharmacology Biochemistry and …, 1991 - Elsevier
… 2[3-carbomethoxy-313-(4-fluorophenyl)tropane (CFT) and … Although the two drugs had
qualitatively similar effects, CFT … the potency relations reported for CFT and cocaine in studies of …

Automated on-line preparation of 11C-β-CFT, a dopamine transporter imaging agent

…, J Tian, Z Guo, W Ding, S Yao, D Yin, B Liu - Chinese Journal of …, 2005 - inis.iaea.org
… C-β-CFT was mainly concentrated in liver, kidney and brain … min after injection, 11 C-β-CFT
was found more sensitive than 11 … in producing 11 C-β-CFT of high radiochemical purity and …

[123I]-2. beta.-carbomethoxy-3. beta.-(4-iodophenyl) tropane: high-affinity SPECT (single photon emission computed tomography) radiotracer of monoamine reuptake …

JL Neumeyer, S Wang, RA Milius… - Journal of medicinal …, 1991 - ACS Publications
… have synthesized and characterized 20carbomethoxy-30-(4-iodophenyl)tropane (3a;
designated as 0-CIT inanalogy to CFT, and recently reported by Boja et al.8 910under the code RTI…

[HTML][HTML] Radiosynthesis of [18F] N-3-fluoropropyl-2-β-carbomethoxy-3-β (4′ methylphenyl) nortropane (FPCMT)

T Chaly Jr, R Matacchieri, R Dahl, V Dhawan… - Applied radiation and …, 1999 - Elsevier
A synthetic procedure for the routine preparation of [ 18 F ] N-3-fluoropropyl-2-β-carbomethoxy-3-β-(4′
methylphenyl) nortropane ( 18 F FPCMT) has been developed. The synthesis is …

11C-CFT-PET in presymptomatic FTDP-17: a potential biomarker predicting onset

L Wu, J Liu, X Feng, J Dong, W Qin… - Journal of …, 2018 - content.iospress.com
… In conclusion, 11 C-CFT-positron emission tomography could be a potential biomarker for …
to determine if 2b-carbomethoxy-3b-(4-trimethylstannylphenyl) tropane ( 11 C-CFT)-PET can …

Synthesis of dopamine transporter imaging agent 11C- β- CFT and its application in the diagnosis of Parkinson's disease

W Hui, LIU Ziyu, BAI Xia, BAO Baoliang, HE Yulin - 分子影像学杂志, 2023 - j-fzyx.com
… -2β-carbomethoxy--(4-flurophenyl) tropanel( 11 C-β-CFT) … online and the precursor
2β-carbomethoxy--(4-flurophenyl) … and the product 11 C-β-CFT was eluted from the C18 column …

Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites

DR Elmaleh, AJ Fischman, TM Shoup… - The Journal of …, 1996 - search.proquest.com
… Previously, we synthesized and evaluated a series of 11C-labeled 2 beta-carbomethoxy-3
beta-aryltropane (WIN 35,428; CFT) derivatives as markers for the dopamine transporter …

Preclinical pharmacological studies of {sup 131} I-FP-{beta}-CIT as dopamine transporter imaging agent

C Zhengping, Z Xiang, D Shiyu, L Yansong… - Nuclear Techniques, 2003 - osti.gov
The {sup 131}I-FP-{beta}-CIT (2{beta}-carbomethoxy-3{beta}-(4-iodophenyl)tropane) was
prepared by ourselves. Its partition coefficients were determined. Kinetics of blood clearance in …

[HTML][HTML] N-4-[18F] Fluorobut-2-yn-1-yl-2β-carbomethoxy--phenyltropane

K Leung - 2011 - europepmc.org
… Binding in the brain was totally blocked in the presence of 1 µM β-CFT. … MZ reduced the
striatum/cerebellum ratio to 5 at 20 min after β-CFT injection. β-CFT was able to displace [ 18 F]…

The feasibility of statistical parametric mapping for the analysis of positron emission tomography studies using 11C-2-β-carbomethoxy-3-β-(4-fluorophenyl)-tropane in …

G Lucignani, C Gobbo, RM Moresco… - Nuclear medicine …, 2002 - journals.lww.com
… Other tracers, eg 11 C-β-CFT and 18 F-β-CFT, have been shown to be more useful for PET
studies but may require several hours to approach binding equilibrium; but the short half-life …