Changes in dopamine availability in the nigrostriatal and mesocortical dopaminergic systems by gait in Parkinson's disease
Y Ouchi, T Kanno, H Okada, E Yoshikawa… - Brain, 2001 - academic.oup.com
… -β-carbomethoxy-3β-(4-fluorophenyl) tropane ([ 11 C]CFT) to investigate changes in [ 11 C]CFT
… Irreversibly bound tracers such as [ 18 F]FDG and [ 11 C]CFT might be suitable to use for …
… Irreversibly bound tracers such as [ 18 F]FDG and [ 11 C]CFT might be suitable to use for …
Reproducibility and Effect of Levodopa on Dopamine Transporter Function Measurements: A [18F]CFT PET Study
E Nurmi, J Bergman, O Eskola, O Solin… - Journal of Cerebral …, 2000 - journals.sagepub.com
… using 2β-carbomethoxy-3β-(4-[ 18 F]-fluorophenyl)tropane ([ 18 F]CFT) positron emission …
on [ 18 F]CFT binding in any striatal subregion in patients with PD. In a previous [ 123 I]β-CIT …
on [ 18 F]CFT binding in any striatal subregion in patients with PD. In a previous [ 123 I]β-CIT …
Efficient HPLC separation of [11C] β-CFT or [11C] β-CIT from an N-desmethyl precursor on a semipreparative reversed phase ODS column
K Kawamura, K Ishiwata, M Futatsubashi, SI Ishii… - Applied Radiation and …, 2000 - Elsevier
… As a DAT blocker, β-CIT (2-β-carbomethoxy-3-β-(4-iodophenyl… β-CFT (WIN 35,428, 2-β-carbomethoxy-3-β-(4-fluorophenyl)…
; NET/DAT, 43.2) than β-CIT. Several analogs labeled with 11 …
; NET/DAT, 43.2) than β-CIT. Several analogs labeled with 11 …
Radiosynthesis of [18F] N-3-fluoropropyl-2-β-carbomethoxy-3-β-(4-iodophenyl) nortropane and the first human study with positron emission tomography
T Chaly, V Dhawan, K Kazumata, A Antonini… - Nuclear medicine and …, 1996 - Elsevier
… Cocaine analogues in which the phenyl moiety is attached directly to the tropane ring by
replacing the benzyl ester group, such as CFT and CIT, have been found to be more potent and …
replacing the benzyl ester group, such as CFT and CIT, have been found to be more potent and …
Synthesis and Characterization of Radioiodinated N-(3-Iodopropen-1-yl)-2. beta.-carbomethoxy-3. beta.-(4-chlorophenyl) tropanes: Potential Dopamine Reuptake Site …
MM Goodman, MP Kung, GW Kabalka… - Journal of medicinal …, 1994 - ACS Publications
… for [3H]-25-carbomethoxy-35-(p-fluorophenyl)tropane (CFT).23 In vitrocharacterization
and … carbomethoxy-35-(p-iodophenyl)tropane ([123I]CIT) in conjunction with SPECT and [UC]CFT …
and … carbomethoxy-35-(p-iodophenyl)tropane ([123I]CIT) in conjunction with SPECT and [UC]CFT …
AAV2-mediated striatum delivery of human CDNF prevents the deterioration of midbrain dopamine neurons in a 6-hydroxydopamine induced parkinsonian rat model
X Ren, T Zhang, X Gong, G Hu, W Ding, X Wang - Experimental neurology, 2013 - Elsevier
… PET analyses with [ 11 C]-2β-carbomethoxy-3β-(4-fluorophenyl)-tropane ([ 11 C]β-CFT)
probes suggested functional recovery of dopaminergic (DA) neurons. Our results indicate that …
probes suggested functional recovery of dopaminergic (DA) neurons. Our results indicate that …
[18F]CFT ([18F]WIN 35,428), a radioligand to study the dopamine transporter with PET: Biodistribution in rats
… min) of 2~-carbomethoxy-3~-(4-fluorophenyl)tropane (also known as CFT or WIN 35,428)
and the biodistribution of this compound in rats. 18F-labelled CFT has high chemical and …
and the biodistribution of this compound in rats. 18F-labelled CFT has high chemical and …
Synthesis of a radiotracer for studying dopamine uptake sites in vivo using PET: 2β‐carbomethoxy‐3β‐(4‐fluorophenyl)‐[N‐11C‐methyl]tropane ([11C]CFT or [11C] …
RF Dannals, JL Neumeyer, RA Milius… - Journal of Labelled …, 1993 - Wiley Online Library
… [11C]CFT from nor-CFT. To facilitate the chromatographic separation of nor-CFT and [ IlCICFT,
… the secondary amine precursor, nor-CFT (30). On semipreparative chromatography, the [ …
… the secondary amine precursor, nor-CFT (30). On semipreparative chromatography, the [ …
Multitracer assessment of dopamine function after transplantation of embryonic stem cell‐derived neural stem cells in a primate model of Parkinson's disease
SI Muramatsu, T Okuno, Y Suzuki, T Nakayama… - Synapse, 2009 - Wiley Online Library
… PET with [11C]2b-carbomethoxy-3b-(4-fluorophenyl)tropane ([11C]b-CFT) was performed
with an additional 19 time frames at 3 min for a total of 91 min. To measure DA release in the …
with an additional 19 time frames at 3 min for a total of 91 min. To measure DA release in the …
Olfactory loss and nigrostriatal dopaminergic denervation in the elderly
KK Wong, MLTM Muller, H Kuwabara, SA Studenski… - Neuroscience …, 2010 - Elsevier
… C]2-β-carbomethoxy-3β-(4-fluorophenyl) tropane (β-CFT) positron … Regional cerebral [ 11
C]β-CFT binding was determined by … 1 shows illustrative examples of [ 11 C]β-CFT DAT PET …
C]β-CFT binding was determined by … 1 shows illustrative examples of [ 11 C]β-CFT DAT PET …