… ~carbomethoxy-3~(4fluorophenyl)tropane (CFl', 2), and a group of dopamine reuptake blockers
… ammonium hydrogen and the carbonyl of the carbomethoxy group. The N-methyl groups …

… with therapeutic doses of selective serotonin reuptake inhibitors (SSRIs). Selective serotonin
reuptake inhibitors also appear to increase the availability of dopamine transporters (DAT). …

… the 3-carbomethoxy-4-(aryl-substituted)piperidine was observed to be a more potent inhibitor
of the human dopamine … Based on the K i (binding) and IC 50 (reuptake inhibition) values …

… that PE2I selectively recognized the dopamine transporter (DAT) according to a …
inhibitor of dopamine uptake, with IC 50 values similar to those for GBR 12909 and 2β-carbomethoxy-3β-…

… is also present in another family of potent and selective DAT inhibitors, namely, the 1,4-…
lead to the discovery of a cocaine antagonist which does not effect dopamine reuptake. …

… as a high affinity ligand for dopamine … [3H]Mazindol binding associated with neuronal
dopamine and norepinephrine … reuptake inhibitors enhance the discriminative …

… dopamine is substantially weaker in inhibiting binding of radiolabeled blockers to the dopamine
… Rothman RB, High affinity dopamine reuptake inhibitors as potential cocaine antagonists…

… N-Substituted analogs of β-CIT (2) with a carbomethoxy ester moiety displayed either
relatively … as mood-elevating clinical drugs by homology to other serotonin-reuptake inhibitors. …

… central dopaminergic system.1, 2, 3 Cocaine binds at the dopamine transporter (DAT) protein
to result in inhibition of dopamine reuptake into … as potent and selective SERT inhibitors. …

The interaction of (E)-N-(3-iodoprop-2-enyl)-2β-Carbomethoxy-3β-(4′-methylphenyl)
nortropane (PE2I) with the rat neuronal dopamine transporter (DAT) was studied in transfected …