… Radioiodine was introduced into the 3Z and 3£-position of jV-(3-iodopropen-l-yl)-2d-carbomethoxy-3j8-(4-chlorophenyl)
tropane by iododemetalation of the corresponding 3-(tri-n-…

Two novel series of iodinated N-substituted analogs of 2β-carbomethoxy-3β-(4‘-iodophenyl)tropane
(β-CIT) and N-(3-iodoprop-(2E)-enyl)-2β-carbomethoxy-3β-(3‘,4‘-disubstituted …

Imaging techniques are increasingly applied to neuro-chemical and neuropharmacological
studies of brain function. PET (positron emission tomography) and SPECT (single photon …

… 3-4 orders of magnitude lower affinity for these two monoamine transporters than the (lfi)-enantiomer
4… of the benzoyl group at C-3 of tropane ring with an aryl group,4 theinversion of(lfi)-…

… The 3′-iodo positional isomer of 2-β-carbomethoxy-3-β-(4′-iodophenyl)tropane (β-CIT)
and other 3′-substituted analogs were synthesized and evaluated for binding to monoamine …

… ][3-CIT and 2[3-carbomethoxy-3[3-(4-iodophenyl)-N(3-fluoropropyl)nortropane ([123I][3-CIT-…
Peak uptake of [123I][3-CIT-FP into the basal ganglia occurred earlier (3-4 h after injection …

… Iodine-123-@3-carbomethoxy-3f3-(4-iodophenyl)tropane SPECT studies also showed a
severe loss of striatal DA transporters in Parkinson's disease, more pronounced in the putamen …

… This report documents the radiation dosimetry of iodine-123 labelled 2fl-carbomethoxy-3fl(4-iodophenyl)tropane
[I23I]fl-CIT in humans. The mean absorbed doses for various organs …

… [ 18 F] labeled-N-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane was prepared
and PET imaging was performed on human subjects. A high uptake into striatal regions was …

… One likely possibility for this contamination could be N-(1-propene-3-yl)2β-carbomethoxy-3β-(4-iodophenyl)nortropane
5b. This product could result from the alkylation of 4 by 3-bromo-1…