Carcinogen-DNA adducts as a biomarker for cancer risk

A Rundle - … Research/Fundamental and Molecular Mechanisms of …, 2006 - Elsevier
… research that seeks to use carcinogen-DNA adducts as means of implicating exposures to
environmental carcinogens in cancer etiology, articles on adducts related to oxidative stress …

[PDF][PDF] DNA adducts of chemical carcinogens

A Dipple - Carcinogenesis, 1995 - Citeseer
carcinogen-DNA adduct formation is complex, most carcinogens either alkylate, arylaminate
or aralkylate DNA… The sites of alkylation and polycyclic aralkylation on DNA do not overlap, …

The role of DNA adducts in chemical carcinogenesis

RC Garner - … Research/Fundamental and Molecular Mechanisms of …, 1998 - Elsevier
… A number of different methods have been developed to detect and measure DNA adducts in
… agents on DNA adduct level. AMS has been used to measure DNA adducts in human tissue …

Carcinogen-DNA adducts in human breast tissue.

FP Perera, A Estabrook, A Hewer, K Channing… - … , biomarkers & prevention …, 1995 - AACR
DNA damage from specific carcinogens directly in human tissue. In this pilot study, a total of
31 breast tissue … adducts have also been associated … Aromatic DNA adducts and an adduct

Postlabeling methods for carcinogen-DNA adduct analysis.

K Randerath, E Randerath, HP Agrawal… - Environmental …, 1985 - ehp.niehs.nih.gov
… In this article a recently developed 32P-postlabeling method for the analysis of carcinogen-…
of carcinogen-DNA adducts, the method is also applicable to carcinogen-RNA adducts. The …

DNA adduct burden and tobacco carcinogenesis

JK Wiencke - Oncogene, 2002 - nature.com
… The inducibility of DNA adductsDNA adducts in tobacco carcinogenesis include numerous
studies showing associations of tobacco smoke exposure with the induction of DNA adducts

Relationships between DNA adduct formation and carcinogenesis.

JA Swenberg, FC Richardson… - Environmental …, 1985 - ehp.niehs.nih.gov
DNA adducts and carcinogenesis. Many of the studies utilized organ specific differences in
carcinogenesis to … This cell specificity in carcinogenesis correlates well with the presence of …

Carcinogens and DNA damage

JL Barnes, M Zubair, K John, MC Poirier… - Biochemical Society …, 2018 - portlandpress.com
… immunostaining in a UK prostate sample stained for carcinogenic PAH-DNA adducts: (left …
stained for carcinogenic PAH-DNA adducts: (left panel) specific PAH-DNA adduct staining is …

Carcinogenic polycyclic aromatic hydrocarbon‐DNA adducts and mechanism of action

WM Baird, LA Hooven… - Environmental and …, 2005 - Wiley Online Library
… environmental carcinogens. Most of our knowledge of their mechanisms of metabolic activation
to DNA-binding ‘‘ultimate carcinogenic’’ metabolites has come from analysis of the DNA

DNA adducts and carcinogenesis

FA Beland, MC Poirier - The Pathobiology of Neoplasia, 1989 - Springer
carcinogen, For each class, we consider the metabolic activation pathways and discuss the
DNA adducts … that result within DNA when these lesions are replicated, and when multiple …