Carcinogen-DNA adducts as a biomarker for cancer risk
A Rundle - … Research/Fundamental and Molecular Mechanisms of …, 2006 - Elsevier
… research that seeks to use carcinogen-DNA adducts as means of implicating exposures to
environmental carcinogens in cancer etiology, articles on adducts related to oxidative stress …
environmental carcinogens in cancer etiology, articles on adducts related to oxidative stress …
[PDF][PDF] DNA adducts of chemical carcinogens
A Dipple - Carcinogenesis, 1995 - Citeseer
… carcinogen-DNA adduct formation is complex, most carcinogens either alkylate, arylaminate
or aralkylate DNA… The sites of alkylation and polycyclic aralkylation on DNA do not overlap, …
or aralkylate DNA… The sites of alkylation and polycyclic aralkylation on DNA do not overlap, …
The role of DNA adducts in chemical carcinogenesis
RC Garner - … Research/Fundamental and Molecular Mechanisms of …, 1998 - Elsevier
… A number of different methods have been developed to detect and measure DNA adducts in
… agents on DNA adduct level. AMS has been used to measure DNA adducts in human tissue …
… agents on DNA adduct level. AMS has been used to measure DNA adducts in human tissue …
Carcinogen-DNA adducts in human breast tissue.
FP Perera, A Estabrook, A Hewer, K Channing… - … , biomarkers & prevention …, 1995 - AACR
… DNA damage from specific carcinogens directly in human tissue. In this pilot study, a total of
31 breast tissue … adducts have also been associated … Aromatic DNA adducts and an adduct …
31 breast tissue … adducts have also been associated … Aromatic DNA adducts and an adduct …
Postlabeling methods for carcinogen-DNA adduct analysis.
K Randerath, E Randerath, HP Agrawal… - Environmental …, 1985 - ehp.niehs.nih.gov
… In this article a recently developed 32P-postlabeling method for the analysis of carcinogen-…
of carcinogen-DNA adducts, the method is also applicable to carcinogen-RNA adducts. The …
of carcinogen-DNA adducts, the method is also applicable to carcinogen-RNA adducts. The …
DNA adduct burden and tobacco carcinogenesis
JK Wiencke - Oncogene, 2002 - nature.com
… The inducibility of DNA adducts … DNA adducts in tobacco carcinogenesis include numerous
studies showing associations of tobacco smoke exposure with the induction of DNA adducts …
studies showing associations of tobacco smoke exposure with the induction of DNA adducts …
Relationships between DNA adduct formation and carcinogenesis.
JA Swenberg, FC Richardson… - Environmental …, 1985 - ehp.niehs.nih.gov
… DNA adducts and carcinogenesis. Many of the studies utilized organ specific differences in
carcinogenesis to … This cell specificity in carcinogenesis correlates well with the presence of …
carcinogenesis to … This cell specificity in carcinogenesis correlates well with the presence of …
Carcinogens and DNA damage
JL Barnes, M Zubair, K John, MC Poirier… - Biochemical Society …, 2018 - portlandpress.com
… immunostaining in a UK prostate sample stained for carcinogenic PAH-DNA adducts: (left …
stained for carcinogenic PAH-DNA adducts: (left panel) specific PAH-DNA adduct staining is …
stained for carcinogenic PAH-DNA adducts: (left panel) specific PAH-DNA adduct staining is …
Carcinogenic polycyclic aromatic hydrocarbon‐DNA adducts and mechanism of action
WM Baird, LA Hooven… - Environmental and …, 2005 - Wiley Online Library
… environmental carcinogens. Most of our knowledge of their mechanisms of metabolic activation
to DNA-binding ‘‘ultimate carcinogenic’’ metabolites has come from analysis of the DNA …
to DNA-binding ‘‘ultimate carcinogenic’’ metabolites has come from analysis of the DNA …
DNA adducts and carcinogenesis
FA Beland, MC Poirier - The Pathobiology of Neoplasia, 1989 - Springer
… carcinogen, For each class, we consider the metabolic activation pathways and discuss the
DNA adducts … that result within DNA when these lesions are replicated, and when multiple …
DNA adducts … that result within DNA when these lesions are replicated, and when multiple …