Mechanisms of multistep carcinogenesis and carcinogen risk assessment.

JC Barrett - Environmental health perspectives, 1993 - ehp.niehs.nih.gov
… in mutagenesis studies for carcinogen risk assessment in the … of these end points in risk
assessment. c) The observations … have significant implications for risk assessment of chemicals. …

Carcinogen risk assessment in the US Environmental Protection Agency

RE Albert - Critical reviews in toxicology, 1994 - Taylor & Francis
… of carcinogens in the … carcinogen risk assessment, the thinking that was behind the formulation
of its methodology, the current status and accomplishments of carcinogen risk assessment

Carcinogenic risk assessment

J Cornfield - Science, 1977 - science.org
… a potential carcinogenic risk and another governing the other three categories. Carcinogenic
… The concept of a saturation dose is relevant to risk assessments for carcinogenic and …

The road to linearity: why linearity at low doses became the basis for carcinogen risk assessment

EJ Calabrese - Archives of toxicology, 2009 - Springer
… low dose from chemical carcinogens was strongly influenced … modeling for risk assessment
for chemical carcinogens with little … policy concerning carcinogen risk assessment. These …

Cellular and molecular mechanisms of multistep carcinogenesis: relevance to carcinogen risk assessment.

JC Barrett, RW Wiseman - Environmental Health Perspectives, 1987 - ehp.niehs.nih.gov
… in carcinogenesis should caution against simplistic models of carcinogen risk assessment
… of this subject, entitled "Multistage Carcinogenesis: Implications for Risk Assessment," by H. …

[PDF][PDF] Proposed guidelines for carcinogen risk assessment

CR Assessment - Federal Register, 1996 - hero.epa.gov
… will be used for Agency carcinogen risk assessment and, in 19 particular, will address the
impact of the Guidelines on the Agency’s existing assessments, and 20 any mechanisms for …

The emperor wears no clothes in the field of carcinogen risk assessment: ignored concepts in cancer risk assessment

JE Trosko, BL Upham - Mutagenesis, 2005 - academic.oup.com
… bioassay to predict risks to human cancers … carcinogenesis that might lead to another
approach for assessing the identification of human carcinogenic hazards and the risk assessment

US Environmental Protection Agency guidelines for carcinogen risk assessment: past and future

J Wiltse, VL Dellarco - Mutation Research/Reviews in Genetic Toxicology, 1996 - Elsevier
… for Carcinogen Risk Assessment. Today, there is a better understanding of the variety of
modes by which carcinogens … of action of carcinogens. In response to the evolving science of …

Risk assessment of chemical carcinogens and thresholds

HG Neumann - Critical reviews in toxicology, 2009 - Taylor & Francis
assessment of non-genotoxic carcinogens. The entry “threshold” in the glossary of the final
report of the German ad hoc Risk … of background burden in risk assessment and emphasizes …

Approaches to the risk assessment of genotoxic carcinogens in food: a critical appraisal

J O'Brien, AG Renwick, A Constable, E Dybing… - Food and Chemical …, 2006 - Elsevier
… for the evaluation of genotoxic carcinogens in food following a … that are genotoxic and
carcinogenic. An additional objective … The risk assessment of genotoxic carcinogens has been …