Overview of biological mechanisms of human carcinogens

N Birkett, M Al-Zoughool, M Bird, RA Baan… - … Environmental Health …, 2019 - Taylor & Francis
carcinogenic mechanisms for 109 Group 1 human carcinogens identified as causes of human
… The International Agency for Research on Cancer (IARC) evaluates human, experimental …

Mechanisms of chemical carcinogenesis and application to human cancer risk assessment

GM Williams - Toxicology, 2001 - Elsevier
… the panel concluded that ‘carcinogenic risk assessment should be done … mechanisms
underlying carcinogenesis’. Thus, the recognition of different mechanisms of action of carcinogens

Cellular and molecular mechanisms of multistep carcinogenesis: relevance to carcinogen risk assessment.

JC Barrett, RW Wiseman - Environmental Health Perspectives, 1987 - ehp.niehs.nih.gov
… by different genetic mechanisms, it is not surprising that a single carcinogen-DNA adduct
or toxicological end point does not always correlate with carcinogenic potency of chemicals. …

… matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms

A Valavanidis, K Fiotakis… - … Science and Health, Part …, 2008 - Taylor & Francis
… With these aspects in mind, future research should aim at establishing a cleared picture
of the cytotoxic and carcinogenic mechanisms of PM in the lungs, as well as mechanisms of …

Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis

MT Smith, KZ Guyton, CF Gibbons… - … health perspectives, 2016 - ehp.niehs.nih.gov
… > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100,
parts … data to support conclusions regarding human hazard from exposure to carcinogens. …

A review on epigenetic effect of heavy metal carcinogens on human health

S Mishra, SP Dwivedi, RB Singh - The open nutraceuticals …, 2010 - benthamopen.com
… critical issue in maintaining the human health. The carcinogenicity of aluminum, arsenic, …
compilation of various studies dealt with epigenetic effects of carcinogens on human health. …

Mechanisms of multistep carcinogenesis and carcinogen risk assessment.

JC Barrett - Environmental health perspectives, 1993 - ehp.niehs.nih.gov
… multigene model of carcinogenesis. In this … carcinogenesis has provided a paradigm by
which chemicals can act by qualitatively different mechanisms, but the process of carcinogenesis

Mechanisms of nongenotoxic carcinogenesis and assessment of the human hazard

BS Lima, JW Van der Laan - Regulatory Toxicology and Pharmacology, 2000 - Elsevier
… The purpose of this paper is to describe some mechanisms for nongenotoxic … a mechanism
is not relevant to humans. The increasing attention being given to epigenetic carcinogenesis

[HTML][HTML] An overview of carcinogenic heavy metal: molecular toxicity mechanism and prevention

HS Kim, YJ Kim, YR Seo - Journal of cancer prevention, 2015 - ncbi.nlm.nih.gov
… Some heavy metals are significant toxicants and carcinogens.1 We discussed the major
sources of exposure, toxicity, and carcinogenic mechanisms of four heavy metals in this review. …

Micro (nano) plastics pollution and human health: How plastics can induce carcinogenesis to humans?

R Kumar, C Manna, S Padha, A Verma, P Sharma… - Chemosphere, 2022 - Elsevier
… dermal exposure, which can cause carcinogenesis, according to Agency for Toxic … humans.
Lastly, this review work concluded with current knowledge on potential risks to human health