[HTML][HTML] The dynamic interplay between cardiac inflammation and fibrosis

TP Thomas, LA Grisanti - Frontiers in physiology, 2020 - frontiersin.org
Inflammation also plays a critical role in the … inflammatory and fibrotic response. This review
discusses the cellular and molecular mechanisms contributing to inflammation and fibrosis

The biological basis for cardiac repair after myocardial infarction: from inflammation to fibrosis

SD Prabhu, NG Frangogiannis - Circulation research, 2016 - Am Heart Assoc
… and molecular signals regulating the inflammatory and reparative response after … inflammation,
perturbed spatial containment of the inflammatory response, and overactive fibrosis may …

Inflammation and fibrosis in murine models of heart failure

L Bacmeister, M Schwarzl, S Warnke, B Stoffers… - Basic research in …, 2019 - Springer
Cardiac fibrosis, however, is characterised by an increased … As evidence exists that cardiac
inflammation and fibrosis are … of the pathogenesis of cardiac inflammation and fibrosis in six …

Cardiac fibrosis

NG Frangogiannis - Cardiovascular research, 2021 - academic.oup.com
Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of extracellular
matrix proteins, is a common pathophysiologic companion of many different myocardial …

The pathogenesis of cardiac fibrosis

P Kong, P Christia, NG Frangogiannis - Cellular and molecular life …, 2014 - Springer
… In other cases, injurious stimuli (such as pressure overload or myocardial inflammation) may
activate pro-fibrotic pathways in the absence of cell death. Several cell types are implicated …

Mechanisms of cardiac fibrosis in inflammatory heart disease

G Kania, P Blyszczuk, U Eriksson - Trends in cardiovascular medicine, 2009 - Elsevier
Inflammatory dilated cardiomyopathy (iDCM) refers to a subtype of dilated cardiomyopathy
characterized by cardiac inflammation, progressively impaired contractility, tissue fibrosis, …

Cardiac fibrosis and inflammation: interaction with hemodynamic and hormonal factors

A Nicoletti, JB Michel - Cardiovascular research, 1999 - academic.oup.com
… arterial tree, and accordingly perivascular inflammation and fibrosis develop in both the left
and … , we hypothesize that perivascular inflammation and fibrosis may be triggered partly by …

[HTML][HTML] Role of cardiac macrophages on cardiac inflammation, fibrosis and tissue repair

WP Lafuse, DJ Wozniak, MVS Rajaram - Cells, 2020 - mdpi.com
… of cardiac macrophages on cardiac inflammation, tissue repair, regeneration and fibrosis. …
cytokines, which results in the induction of cardiac fibrosis and cardiac hypertrophy [59]. In …

Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities

NG Frangogiannis - Molecular aspects of medicine, 2019 - Elsevier
… specific aspects of the fibrotic response. Secreted fibrogenic … regulation of fibrosis are critical
for cardiac repair and may … forms of cardiac fibrosis, targeting fibrotic remodeling following …

The role of cardiac fibroblasts in the transition from inflammation to fibrosis following myocardial infarction

FA van Nieuwenhoven, NA Turner - Vascular pharmacology, 2013 - Elsevier
… In the maturation phase, inflammation is reduced by anti-inflammatory cytokines, and …
cardiac dilation. In this review we discuss the transition from myocardial inflammation to fibrosis