… supporting this role of cytosolic Ca2+. These data include the demonstration that mitochondrial
[Ca2+] can track cytosolic [Ca2+] and that the compartmentation of cytosolic [Ca2+] can …

… Here, we discuss how these pathways relate to the cardiac metabolism and how they …
function: cyclic AMP as a messenger of β-adrenergic pathway and Ca 2+ as a mediator of excitation…

… modify cardiac metabolism and elucidate their roles in the development of cardiomyopathy.
… by ion transporters (like Ca 2+ -ATPase), inhibition of cardiac glycolysis impairs intracellular …

… a mechanistic mathematical model that integrates cardiac metabolism with the regulation of
… the role of Ca 2+ in the regulation of cardiac energetics. The study investigates whether Ca 2…

… In HF, it is well established that altered functional expression of SERCA2 plays an
important role in abnormal Ca 2+ homeostasis; however the mechanisms underlying SERCA2 …

… role in regulating Ca2+ uptake and cardiac muscle contraction. … light chain of cardiac
myosin? Does calmodulin play a role in the heart in the regulation of glycogen metabolism …

… an increase in cytoplasmic Ca 2+ , are obtained when the Ca 2+ -sensitive dehydrogenases
… Ca 2+ plays an important role in matching energy supply with demand in cardiac myocytes. …

… cardiac RYR2, using a conditional gene knock-out strategy (cRyr2KO mice), is sufficient to
reduce mitochondrial Ca 2+ and oxidative metabolism… a causal, upstream role for this channel …

… cardiac fuel metabolism under pathological conditions followed by recent progress on targeting
cardiac metabolism … In addition, we summarize the emerging role of cardiac metabolism …

… long-term regulation of cardiac metabolism is very limited. In view of their central role in the
body’… to minimize the disturbances in Ca2+ homeostasis associated with cardiac hypertrophy. …