… nodes or pathways that govern cardiac morphogenesis and perturbation of these pathways
… in the developing mouse heart. Gene disruption of the Hand2 gene resulted in embryonic …

… Focusing on an established cardiac Hand2 cistrome, we observe selective reorganization of
… -specific gene expression. Moreover, we identify a Hand2 cardiac subtype diversity (CSD) …

… , differentiation and cardiac morphogenesis. During … Hand2 right ventricular myocardial
expression correlates … to determine which genes are regulated directly by Hand2, and …

… abnormal segments between HAND1 and HAND2. So, the … the morphogenesis of the
particular components in the heart. … the outcome of the HAND1/HAND2 gene in the cells (Figure …

… of Hand2as might promote HAND2 expression and heart morphogenesis in the promoter
and … of Hand2as and HAND2, we found that 6 genes were expressed in at least one type of …

… heart, vascular system, facies, limb, and various neural crest-derived structures. In this study,
genes whose expression was affected in hearts of Hand2 … the known effects of HAND2. One …

… landscapes encode heart and limb bud specific CRMs bound by HAND2 chromatin … cellular
hierarchies and lineages relationships of the cardiac cells with associated genetic marker(s). …

… known to drive cardiac growth and morphogenesis through primary heart field development…
HAND2 gene expression, which is known to preferentially control right heart morphogenesis …

… for placentation and cardiac morphogenesis. Nat Genet1998 ; … and morphogenesis in the
developing mammalian heart. Dev … tion factor hand2 plays parallel roles in zebrafish heart and …

… heart field and formation of the cardiac crescent. In some cases, maintained expression of
these genes is crucial for the later stages of cardiac morphogenesis… genetic deletion of Hand2 …