… , HAND2 activated the angiogenesis-related gene Aggf1. … These differentially expressed
genes were primarily involved … and tube morphogenesis, adult heart development, and cardiac …

… Proper cardiac morphogenesis requires a series of specific … cardiac transcription factors and
downstream cardiac genes. … This study implies that Hand2 is required for vascular and heart …

… Similarly, we isolated CMs from cardiac TF mutants of gata5, tbx5a, and hand2 at 72 hpf. We
… of cardiac genes involved in heart morphogenesis, we identified gene regulatory networks …

… In the present study, we showed that Hand2 represses chondrogenesis and chondrocyte
gene expression in the limb-bud mesenchyme assay. Consistent with this observation, …

… has indicated its important role during the morphogenesis of … factors in cardiac patterning,
cardiac morphogenesis, and the … allele and cardiac-specific gene excision together with Hand2 …

… cardiac morphogenesis include the activation and expression of a several cardiac gene …
interaction with the Hand2 cardiac enhancer negatively affectsHand2 transcription, preventing …

… In this study, the entire coding region and splicing boundaries of the HAND2 gene … Hand2
plays pivotal roles in cardiovascular morphogenesis, and the imbalanced dosage of HAND2 …

… factor Hand2 and is expressed in the migrating myocardial cells 67 ). The han/ hand2 gene
seems to regulate both the differentiation and the morphogenesis of the myocardial cells and …

… show that Hand2, a transcription factor that promotes ventricular cardiomyocyte expansion,
is a target of miR-1. This work suggests that miR-1 genes titrate the effects of critical cardiac …

… Cardiac morphology shows that cardiac morphogenesis is comparable to both Hand1
hypomorph and Hand2 … these data suggest genetic interactions within the developing heart, given …