… with dilated or hypertrophic cardiomyopathy. Through its … role in the pathogenesis of cardiac
remodeling and fibrosis. TGF-… pathogenesis of cardiac fibrotic and hypertrophic remodeling, …

… includes well-known regulators of cardiomyocyte hypertrophy, but apart from Gata4, they
are not known to participate in a proliferative phenotype, such as we see with C/EBPβ reduction…

… For example, placental growth factor (PlGF) has recently … modifications, increasing
cardiomyocyte growth and contractility [158]. … used to reduce adverse cardiac remodeling, …

… This study provides evidence that cardiac remodeling induced by FGR persists … cardiac
programming in FGR for explaining the association between low birth weight and cardiovascular …

… Cardiac remodeling is generally accepted as a determinant of … heart resulting from cardiac
load or injury, cardiac remodeling is … at correcting a low cardiac output or reduced blood flow—…

… Hence, cardiac remodeling leads to reduced calcium release during systole and increased
… Other effects reported include activation of growth factors and metalloproteinases, …

… through the activation and release of growth factors and other bioactive peptides bound to
… of cardiac remodeling. Indeed, we determined that TIMP-3 expression is reduced in human …

… Next, we examined the effect of cardiac remodeling on tumor growth in male mice using
a … a typical cardiac remodeling phenotype as appreciated by reduced contractile function, …

… and molecular remodeling such as myocyte growth without significant … in reduced myocardial
capillary density, accelerated contractile dysfunction, and pathological cardiac remodeling. …

… cardiac remodeling at 6 months of age, it remains to be determined whether there is a direct
association with cardiovascular … reduce the probability of cardiovascular disease later in life. …