[HTML][HTML] TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways

SB Haudek, GE Taffet, MD Schneider… - The Journal of clinical …, 2007 - Am Soc Clin Investig
cell death pathway in the adverse cardiac remodeling that we observed in the MHCsTNF
mice. To determine whether cardiac … , the results of this study provide several new insights into …

Molecular pathways underlying cardiac remodeling during pathophysiological stimulation

I Kehat, JD Molkentin - Circulation, 2010 - Am Heart Assoc
cell death in the context of hypertrophy, 79,80 underlying the importance of cell death in
ventricular remodeling and … appear be very important for autophagic cell death and hypertrophy. …

A review of the molecular mechanisms underlying the development and progression of cardiac remodeling

L Schirone, M Forte, S Palmerio, D Yee… - … and cellular …, 2017 - Wiley Online Library
pathways involved in cardiac remodeling, with particular emphasis on those associated with
myocardial … Progressive cell death in the chronically overloaded heart is considered among …

Role of cell death in the progression of heart failure

GW Moe, J Marín-García - Heart failure reviews, 2016 - Springer
… Besides ROS-mediated damage and cell death leading to cardiac remodeling and eventually
to HF, other processes in mitochondria may affect the development and progression of this …

Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling

GW Dorn - Cardiovascular research, 2009 - academic.oup.com
multiple forms of programmed cell death and their overlapping death signalling pathways
you target the suicidal proclivities of cardiac myocytes without producing untoward effects on …

The interplay between cell death signaling pathways in the heart

AK Biala, LA Kirshenbaum - Trends in cardiovascular medicine, 2014 - Elsevier
… of the body that retain the ability for regeneration and self-renewal, cardiaccardiac cells
has been suggested as an underlying feature of ventricular remodeling and diminished cardiac

The role of Nrf2‐mediated pathway in cardiac remodeling and heart failure

S Zhou, W Sun, Z Zhang… - … medicine and cellular …, 2014 - Wiley Online Library
… Programmed cell death (apoptosis) of cardiomyocytes has been identified as an … apoptosis
[40]. Taken together, ROS play an important role in the development of cardiac remodeling

Mechanisms contributing to cardiac remodelling

QQ Wu, Y Xiao, Y Yuan, ZG Ma, HH Liao, C Liu… - Clinical …, 2017 - portlandpress.com
… activated UPR generates cell death mainly via extrinsic and intrinsic apoptotic pathways [84].
UPR has been found to be related to many cardiac functions in several disorders including …

Pathological ventricular remodeling: mechanisms: part 1 of 2

JS Burchfield, M Xie, JA Hill - Circulation, 2013 - Am Heart Assoc
… load, multiple molecular and cellular processes contribute to ventricular remodeling. These
include cardiomyocyte loss through cell death pathways such as necrosis, apoptosis, or …

Fundamental mechanisms of regulated cell death and implications for heart disease

DP Del Re, D Amgalan, A Linkermann… - Physiological …, 2019 - journals.physiology.org
… We do not discuss entotic cell death, NETotic cell death, or lysosome-dependent cell death.
… have not been demonstrated to mediate the demise of cardiac cells, and NETotic cell death