Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor
N Sivasubramanian, ML Coker, KM Kurrelmeyer… - Circulation, 2001 - Am Heart Assoc
… ) with cardiac restricted overexpression of TNF that develop progressive LV dilation/remodeling
from 4 to 12 weeks of age. During the early phases of LV structural remodeling, there …
from 4 to 12 weeks of age. During the early phases of LV structural remodeling, there …
Impaired protein quality control during left ventricular remodeling in mice with cardiac restricted overexpression of tumor necrosis factor
J Hartupee, GD Szalai, W Wang, X Ma… - Circulation: Heart …, 2017 - Am Heart Assoc
… cardiomyopathy driven by cardiac restricted overexpression … ubiquitin-tagged proteins within
cardiac myocytes related to … from patients with end-stage heart failure. Moreover, there was …
cardiac myocytes related to … from patients with end-stage heart failure. Moreover, there was …
Cardiac-restricted overexpression of membrane type-1 matrix metalloproteinase in mice: effects on myocardial remodeling with aging
FG Spinale, GP Escobar, R Mukherjee… - Circulation: Heart …, 2009 - Am Heart Assoc
… Left ventricular (LV) remodeling is generically defined as changes in myocardial …
Although the LV remodeling process evokes changes within both the cellular and extracellular …
Although the LV remodeling process evokes changes within both the cellular and extracellular …
Cardiac-restricted overexpression or deletion of tissue inhibitor of matrix metalloproteinase-4: differential effects on left ventricular structure and function following …
WM Yarbrough, C Baicu, R Mukherjee… - … Physiology-Heart …, 2014 - journals.physiology.org
… with left ventricular (LV) dysfunction and matrix remodeling … the hypothesis that cardiac-specific
overexpression (TIMP-… = 25), whereby indexes of LV remodeling and function such as LV …
overexpression (TIMP-… = 25), whereby indexes of LV remodeling and function such as LV …
Cardiac-restricted overexpression of extracellular matrix metalloproteinase inducer causes myocardial remodeling and dysfunction in aging mice
JA Zavadzkas, RA Plyler, S Bouges… - … Physiology-Heart …, 2008 - journals.physiology.org
… The matrix metalloproteinases (MMPs) play a pivotal role in adverse left ventricular (LV)
myocardial remodeling. The transmembrane protein extracellular MMP inducer (EMMPRIN) …
myocardial remodeling. The transmembrane protein extracellular MMP inducer (EMMPRIN) …
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial …
S Janssens, P Pokreisz, L Schoonjans… - Circulation …, 2004 - Am Heart Assoc
… of cardiac performance and left ventricular (LV) remodeling after … cardiac-restricted
overexpression of endothelial NOS preserves cardiac function and limits deleterious left ventricular …
overexpression of endothelial NOS preserves cardiac function and limits deleterious left ventricular …
Cardiac restricted overexpression of membrane type-1 matrix metalloproteinase causes adverse myocardial remodeling following myocardial infarction
FG Spinale, R Mukherjee, JA Zavadzkas… - Journal of biological …, 2010 - ASBMB
… overexpression (MT1-MMPexp), in a left ventricular (LV) remodeling process such as
myocardial … MI was then induced in mice with cardiac restricted MT1-MMPexp (n = 58) and wild …
myocardial … MI was then induced in mice with cardiac restricted MT1-MMPexp (n = 58) and wild …
MCIP1 overexpression suppresses left ventricular remodeling and sustains cardiac function after myocardial infarction
E van Rooij, PA Doevendans, HJGM Crijns… - Circulation …, 2004 - Am Heart Assoc
… MI cardiac remodeling, using a genetic mouse model with mild myocyte-restricted overexpression
of MCIP1, which was previously shown to efficiently antagonize cardiac hypertrophy in …
of MCIP1, which was previously shown to efficiently antagonize cardiac hypertrophy in …
Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice
T Shiomi, H Tsutsui, H Matsusaka, K Murakami… - Circulation, 2004 - Am Heart Assoc
… On the basis of these findings, it is conceivable to hypothesize that increased myocardial …
remodeling. In conclusion, GSHPx overexpression inhibited the development of LV remodeling …
remodeling. In conclusion, GSHPx overexpression inhibited the development of LV remodeling …
Left ventricular remodeling leads to heart failure in mice with cardiac‐specific overexpression of VEGF‐B167: echocardiography and magnetic resonance imaging …
L Lottonen‐Raikaslehto, R Rissanen… - Physiological …, 2017 - Wiley Online Library
… We showed that left ventricular remodeling is already ongoing at the age of 5 months in …
that cardiac‐specific overexpression of VEGF ‐B 167 leads to left ventricular remodeling at early …
that cardiac‐specific overexpression of VEGF ‐B 167 leads to left ventricular remodeling at early …
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