TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways

SB Haudek, GE Taffet, MD Schneider… - The Journal of clinical …, 2007 - Am Soc Clin Investig
… leads to activation of multiple cell death pathways that contribute to progressive
cardiomyocyte apoptosis; hence the extent of such programmed myocyte cell death is a critical …

Signaling pathways in cardiac myocyte apoptosis

P Xia, Y Liu, Z Cheng - BioMed research international, 2016 - Wiley Online Library
… of cardiomyocyte apoptosis by multiple signaling molecules and pathways, with a focus on
the involvement of these pathways in the … Here we focus on the apoptotic form of cell death. …

“How do cardiomyocytes die?” apoptosis and autophagic cell death in cardiac myocytes

S Kunapuli, S Rosanio, ER Schwarz - Journal of cardiac failure, 2006 - Elsevier
… the possible involvement of autophagic cell death in loss of cardiac myocytes. In the … apoptosis
and autophagic cell death, with special interest given to their roles in myocardial cell death

Cell death in the cardiac myocyte

T Marunouchi, K Tanonaka - Biological and Pharmaceutical Bulletin, 2015 - jstage.jst.go.jp
… mitochondrial pathway of apoptotic cell death, release of cytochrome c in cardiac
myocytes … Activation of the mitochondrial pathway has also been implicated in ischemia/reperfusion …

STRESS signaling pathways that modulate cardiac myocyte apoptosis

CP Baines, JD Molkentin - Journal of molecular and cellular cardiology, 2005 - Elsevier
… -responsive signaling pathways, which serve as … pathways have also been implicated
in affecting the decision of myocytes to either survive or undergo programmed cell death (apoptosis

Signaling pathways in reactive oxygen species–induced cardiomyocyte apoptosis

R von Harsdorf, PF Li, R Dietz - Circulation, 1999 - Am Heart Assoc
… We hypothesized that exposure to ROS might lead to cell death through the induction of
apoptosis in cardiac cells. As determined by cell-death detection ELISA, which specifically …

Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies

M Zhang, D Methot, V Poppa, Y Fujio, K Walsh… - … of molecular and cellular …, 2001 - Elsevier
… were often isolated from host cells by scar tissue.… that rat neonatal cardiomyocytes transplanted
into has quantified the size of myocardial grafts, determined how many cells are required …

Cardiomyocyte apoptotic cell death in arterial hypertension: mechanisms and potential management

MA Fortuño, S Ravassa, A Fortuño, G Zalba, J Díez - Hypertension, 2001 - Am Heart Assoc
Many observations point to the apoptotic cell death of cardiomyocytes as a relevant factor in
… Potential inducers of cardiomyocyte apoptosis in overloaded hearts include extrinsic factors, …

Cardiomyocyte death: mechanisms and translational implications

M Chiong, ZV Wang, Z Pedrozo, DJ Cao… - Cell death & …, 2011 - nature.com
cardiac myocyte. However, because mitochondria can also contribute to cell death in response
to multiple stresses, cardiac myocytes … strict control over the intrinsic apoptotic pathway. …

Small molecules, big effects: the role of microRNAs in regulation of cardiomyocyte death

J Skommer, I Rana, FZ Marques, W Zhu, Z Du… - Cell death & …, 2014 - nature.com
… cardiac cell death/cell survival pathways, including apoptosis, … behind the pathogenesis
of many cardiac diseases, and, … that will limit cardiomyocyte cell death before it irreversibly …