Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia

H He, HL Li, A Lin, RA Gottlieb - Cell Death & Differentiation, 1999 - nature.com
pathway from multiple cascades involved in the cellular … of the JNK signaling pathway in
cardiomyocytes under simulated … -1 reduces cell death in isolated cardiomyocytes subjected to …

Catecholamine‐induced apoptosis and necrosis in cardiac and skeletal myocytes of the rat in vivo: the same or separate death pathways?

DF Goldspink, JG Burniston, GM Ellison… - Experimental …, 2004 - Wiley Online Library
… axes of the ventricles Cardiomyocyte apoptosis (□) and … different death pathways as yet
unresolved. Indeed, the fact that we have not investigated the incidence of autophagic cell death

Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo

S Levrand, C Vannay-Bouchiche, B Pesse… - Free Radical Biology …, 2006 - Elsevier
… to trigger cardiomyocyte apoptosis, a crucial mode of cell death in many cardiac conditions,
remains poorly defined. We evaluated apoptotic and necrotic cell death in cultured H9C2 …

Programmed necrosis in cardiomyocytes: mitochondria, death receptors and beyond

J Zhang, D Liu, M Zhang… - British journal of …, 2019 - Wiley Online Library
… that necroptosis plays an important role in cardiomyocyte death and is a major form of cell
death in acute viral myocarditis. Thus, blocking the necroptosis pathway may serve as a new …

Cardiomyocyte life-death decisions in response to chronic β-adrenergic signaling

RS Whelan, K Konstantinidis, RP Xiao… - Circulation …, 2013 - Am Heart Assoc
… It is possible that the higher levels of cytosolic Ca 2+ in unpaced isolated murine
cardiomyocytes 15 lower the threshold for cell death, thereby bypassing the requirement for PKA. …

A model for cardiomyocyte cell death: insights into mechanisms of oncosis

P Weerasinghe, S Hallock, RE Brown, DS Loose… - … and molecular pathology, 2013 - Elsevier
apoptosis using multiple cell death assays. In … apoptosis in cardiomyocytes, we performed
high density microarray analysis on RNAs prepared from cultured mouse cardiomyocytes

[PDF][PDF] Cardiac myocyte apoptosis

SA Cook, PA Poole-Wilson - European Heart Journal, 1999 - Citeseer
apoptotic cell death and the methods used to identify … apoptotic cell death in cardiac myocytes.
Oxidative stress that occurs during reperfusion injury has been shown to induce apoptosis

Apoptosis in cardiac diseases: stress-and mitogen-activated signaling pathways

GZ Feuerstein, PR Young - Cardiovascular research, 2000 - academic.oup.com
… In this review, apoptosis represents the cellular phenotype resulting from activation of genomic
programs that lead to DNA damage and cell death. Reports on cardiomyocyte apoptosis

Mechanistically distinct steps in the mitochondrial death pathway triggered by oxidative stress in cardiac myocytes

M Akao, B O'Rourke, Y Teshima… - Circulation …, 2003 - Am Heart Assoc
… These data reveal that both apoptotic and necrotic cell death occur under our experimental
… In the present study, we used H 2 O 2 -induced cell death in neonatal cardiac myocytes as a …

Regulation of cell death in the cardiovascular system

P Patel, J Karch - International review of cell and molecular biology, 2020 - Elsevier
cell death is multifaceted and employees various degrees of regulation. We will explore all
of the cell death pathways … role and mechanisms of cardiomyocyte cell death in heart failure, …