The cardioprotective effects of citric acid and L‐malic acid on myocardial ischemia/reperfusion injury

X Tang, J Liu, W Dong, P Li, L Li, C Lin… - Evidence‐Based …, 2013 - Wiley Online Library
… Thus, after an initial investigation of the effects of citric acid and L-malic acid on myocardial
cardioprotective effects in cellular level. The concentrations of citric acid and L-malic acid (…

Cardioprotective Effects of Malus Domestica (Apple) May be Mediated Through Antiplatelet, Calcium Channel Blocking, and Antioxidant Properties

R Nawaz, H Ishtiaq, TH Anwar - Phytopharmacological …, 2022 - rootspress.org
… amino acids Cysteine and arginine, as well as malic acid, present in apples have the ability
… The anti-inflammatory effects of these substances serve to counter gout, uric acid, urticarial …

Comparison of cardioprotective abilities between the flesh and skin of grapes

M Falchi, A Bertelli, R Lo Scalzo… - Journal of agricultural …, 2006 - ACS Publications
… the carbohydrates and or organic acids, which were present in both in skin and in flesh.
Especially, tartaric acid and malic acid show a significant ROS scavenging activity against • OH. …

[HTML][HTML] Metabolomics based mechanistic insights to vasorelaxant and cardioprotective effect of ethanolic extract of Citrullus lanatus (Thunb.) Matsum. & Nakai. seeds …

F Saqib, M Wahid, AA Al-Huqail, HT Ahmedah, N Bigiu… - Phytomedicine, 2022 - Elsevier
… The present work used in vitro, in vivo, and molecular docking models to investigate the
cardioprotective properties and metabolomics insights of Citrullus lanatus (Thunb.) Matsum. & …

Citric acid cycle intermediates in cardioprotection

G Czibik, V Steeples, A Yavari… - Circulation …, 2014 - Am Heart Assoc
… et al 48 would not suffice to account for the cardioprotective effect completely. Furthermore,
the cardioprotective influence observed with exogenous nonesterified fumarate in adult rat …

Protective effects of L‐malate against myocardial ischemia/reperfusion injury in rats

S Ding, Y Yang, J Mei - Evidence‐Based Complementary and …, 2016 - Wiley Online Library
cardioprotective effects have been studied but few have made it to clinical use, perhaps due
to animal model choices for studying drug effects as well as myriad side effects … L-malic acid

[PDF][PDF] Cardio-protective effect of Thiamine and Pyridoxine loaded Vanillic acid grafted Chitosan micro-particles against Isoproterenol-induced myocardial Infarction in …

CS Tejpal, K Elavarasan, RGK Lekshmi… - Fishery …, 2021 - drs.cift.res.in
cardio-protective effect of dietary supplementation of thiamine and pyridoxine loaded vanillic
acid … The possible role of dietary TPVGC on cardioprotective effect was assessed in terms of …

In vitro Enzyme Inhibition and In vivo Anti-hyperuricemic Potential of Malic Acid: An Experimental Approach

V Vijeesh, A Vysakh, N Jisha… - Journal of Biologically …, 2022 - Taylor & Francis
… with varying concentrations of malic acid were incubated at room … for XO with malic acid and
XO without malic acid. Three … generation and its least side effects, the malic acid had to get a …

Transcriptomics and metabolomics reveal the cardioprotective effect of Compound Danshen tablet on isoproterenol-induced myocardial injury in high-fat-diet fed mice

P Wu, Z Zhang, G Ma, J Li, W Zhou - Journal of ethnopharmacology, 2020 - Elsevier
… Administration of Compound Danshen tablet significantly attenuated the up-regulation of
lactic acid, malic acid, and L-glutamic acid. Additionally, administration of Compound Danshen …

Mechanism of cardioprotective effect of orotic acid

FL Rosenfeldt, SM Richards, Z Lin, S Pepe… - … drugs and therapy, 1998 - Springer
… The slices were placed in phosphate-buffered saline and stained in nitro-blue tetrazolium
[22] and malic acid substrate. The stain was developed for 15 minutes at 37C, and the …