Cardiovascular effects of glucagonlike peptide1 agonists

MH Davidson - The American journal of cardiology, 2011 - Elsevier
… , patients with diabetes experience increased cardiovascular (CV) events correlated with …
arm of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) 1 trial due to increased …

The cardiovascular biology of glucagon-like peptide-1

DJ Drucker - Cell metabolism, 2016 - cell.com
… Here we review how GLP-1 and clinically approved GLP-1R agonists engage … cardiovascular
disease. We discuss how GLP-1R agonists modify inflammation, cardiovascular physiology…

Mechanisms for the cardiovascular effects of glucagon‐like peptide1

H Poudyal - Acta Physiologica, 2016 - Wiley Online Library
… for GLP-1 in response to nutrients, the expression of GLP-1 receptor in various tissues and
the direct and indirect cardiovascular actions of GLP-1. GLP-1's action in the central nervous …

Cardiovascular actions and clinical outcomes with glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors

MA Nauck, JJ Meier, MA Cavender, M Abd El Aziz… - Circulation, 2017 - Am Heart Assoc
… nor decreased cardiovascular events. Here we review the cardiovascular actions of GLP-1R …
of the potential mechanisms that underlie the cardiovascular benefit and safety of these …

Emerging cardiovascular actions of the incretin hormone glucagon‐like peptide1: potential therapeutic benefits beyond glycaemic control?

DJ Grieve, RS Cassidy… - British journal of …, 2009 - Wiley Online Library
… glucose-lowering actions, GLP-1 may also exert several beneficial actions on the cardiovascular
system. This review will discuss the emerging cardiovascular actions of GLP-1 and its …

Cardiovascular effects of glucagon-like peptide 1 (GLP-1) receptor agonists

FK Saraiva, AC Sposito - Cardiovascular Diabetology, 2014 - Springer
peptide-1 receptor agonists represent a novel class of anti-hyperglycemic agents that have a
cardiac… the multifactorial cardiovascular effects of glucagon-like peptide-1 receptor agonists …

Cardiovascular actions of incretin-based therapies

JR Ussher, DJ Drucker - Circulation research, 2014 - Am Heart Assoc
… a broad range of overlapping and unique cardiovascular actions. Native GLP-1 regulates
cardiovascular biology via activation of the classical GLP-1R, or through GLP-1(9–36), a …

The effect of glucagon-like peptide 1 on cardiovascular risk

J Sivertsen, J Rosenmeier, JJ Holst… - Nature Reviews …, 2012 - nature.com
… Glucagon-like peptide 1 (GLP-1) is an incretin hormone responsible for amplification of
insulin secretion when nutrients are given orally, as opposed to intravenously, and it retains its …

Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms of action

JR Ussher, DJ Drucker - Nature Reviews Cardiology, 2023 - nature.com
action for GLP1R agonist-mediated cardioprotection, which could have therapeutic potential
in a range of cardiovascular … preserving the beneficial cardiovascular actions of structurally …

Cardiovascular actions of parathyroid hormone and parathyroid hormone-related peptide

KD Schlüter, HM Piper - Cardiovascular research, 1998 - academic.oup.com
… of a given peptide hormone may vary among target cells. This review summarizes the present
knowledge about the action of PTH and PTH-rP on cardiovascular target cells with a focus …