L-733,060, a novel tachykinin NK1 receptor antagonist; effects in [Ca2+] i mobilisation, cardiovascular and dural extravasation assays
GR Seabrook, SL Shepheard, DJ Williamson… - European journal of …, 1996 - Elsevier
… lective antagonist of human tachykinin NK~ … human tachykinin NK~ receptors than the rat
(Beresford et al., 1991). Therefore, if the cardiovascular effects of L-733,060 involved tachykinin …
(Beresford et al., 1991). Therefore, if the cardiovascular effects of L-733,060 involved tachykinin …
Tachykinins and their functions in the gastrointestinal tract
Y Shimizu, H Matsuyama, T Shiina, T Takewaki… - Cellular and Molecular …, 2008 - Springer
… that non-cholinergic transmission could be antagonized by desensitization of tachykinin
receptors, or by peptide analog with tachykinin receptor antagonist properties [13 – 17]. …
receptors, or by peptide analog with tachykinin receptor antagonist properties [13 – 17]. …
[HTML][HTML] Expression and function of human hemokinin-1 in human and guinea pig airways
S Grassin-Delyle, E Naline, A Buenestado, PA Risse… - Respiratory …, 2010 - Springer
… tachykinins, tachykinin receptors and tachykinins degrading enzyme neutral endopeptidase
(NEP) mRNAs, and hHK-1 protein in human … : human tachykinins with cardiovascular activity…
(NEP) mRNAs, and hHK-1 protein in human … : human tachykinins with cardiovascular activity…
Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation
… and effective, many patients still experience cardiovascular problems, which may reflect the
… In this study, we define a role for peripherally distributed members of the tachykinin family of …
… In this study, we define a role for peripherally distributed members of the tachykinin family of …
Tachykinins and central respiratory activity: an in vitro study on the newborn rat
R Monteau, K Ptak, N Broquère, G Hilaire - European journal of …, 1996 - Elsevier
… of tachykinins on the activity of the respiratory rhythm generator in vitro and to characterize
the receptors involved. Substance P and tachykinin … affected by the tachykinin NK 2 receptor …
the receptors involved. Substance P and tachykinin … affected by the tachykinin NK 2 receptor …
Sodium cromoglycate: evidence of tachykinin antagonist activity in the human skin
DC Crossman, MR Dashwood… - Journal of Applied …, 1993 - journals.physiology.org
… the use of human skin as an experimental system. In addition, the effect of SCG on the binding
of ‘Y-labeled SP to tissues from the central nervous and cardiovascular systems has been …
of ‘Y-labeled SP to tissues from the central nervous and cardiovascular systems has been …
Neuropeptides as regulators of airway function: vasoactive intestinal peptide and the tachykinins.
CA Maggi, A Giachetti, RD Dey… - Physiological …, 1995 - journals.physiology.org
… SP in causing contraction of human isolated airways, because … Tachykinins also contract
guinea pig lung parenchymal strips, but at a lower potency than central airways (568). In human …
guinea pig lung parenchymal strips, but at a lower potency than central airways (568). In human …
Effect of a tachykinin NK2 receptor antagonist, nepadutant, on cardiovascular and gastrointestinal function in rats and dogs
S Giuliani, M Guelfi, M Toulouse, L Buéno… - European journal of …, 2001 - Elsevier
… We conclude that tachykinin NK 2 receptors do not participate in the physiologic regulation
of resting cardiovascular and … The cardiovascular changes induced by the nonpeptide …
of resting cardiovascular and … The cardiovascular changes induced by the nonpeptide …
Role of substance P in the cardiovascular system
E Mistrova, P Kruzliak, MC Dvorakova - Neuropeptides, 2016 - Elsevier
… cardiovascular regulation. Substance P is an undecapeptide originating from TAC1 gen and
belonging to the tachykinin … systems as well as in the cardiovascular system. Substance P is …
belonging to the tachykinin … systems as well as in the cardiovascular system. Substance P is …
In vivo characterization of the effects of human hemokinin-1 and human hemokinin-1 (4-11), mammalian tachykinin peptides, on the modulation of pain in mice
CY Fu, YL Zhao, L Dong, Q Chen, JM Ni… - Brain, Behavior, and …, 2008 - Elsevier
… Human hemokinin-1 (h HK-1) and its truncated form h HK-1(4-11) are mammalian
tachykinin peptides encoded by the recently identified TAC4 gene in human, and the biological …
tachykinin peptides encoded by the recently identified TAC4 gene in human, and the biological …