Natural antibodies against phosphorylcholine in cardiovascular disease

U De Faire, J Frostegård - Annals of the New York Academy of …, 2009 - Wiley Online Library
… mouse antibodies against oxLDL recognize PC. EO6 is an IgM monoclonal antibody derived
from apoE-deficient mice that was shown to be equivalent to the TI5 natural antibody that …

Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease

J Frostegård - Clinical immunology, 2010 - Elsevier
… their existence as natural antibodies has been known … antibodies against oxLDL named
EO6, recognize PC and the antigen binding site is identical to the ‘classical’ TI5 natural antibody. …

Carotid atherosclerosis, disease measures, oxidized low-density lipoproteins, and atheroprotective natural antibodies for cardiovascular disease in early rheumatoid …

S Ajeganova, ULF de Faire, T Jogestrand… - The Journal of …, 2012 - jrheum.org
… As well, low levels of natural antibodies such as IgM anti-PC during the first 5 years of RA
disease characterized patients with subsequent CVD events, which extends the evidence of …

[HTML][HTML] Can antibodies protect us against cardiovascular disease?

J Nilsson - EBioMedicine, 2016 - thelancet.com
… because expression of antibodies that react with the wrong self-antigens may cause
autoimmune disease. The possible role of antibodies in cardiovascular disease has attracted …

[HTML][HTML] Thematic review series: The Immune System and Atherogenesis. The role of natural antibodies in atherogenesis

CJ Binder, PX Shaw, MK Chang, A Boullier… - Journal of lipid …, 2005 - ASBMB
Natural antibodies can be considered humoral factors of innate immunity, and their functional
role in health and disease has been reexamined in recent years. Natural antibodies exhibit …

Correlation of natural autoantibodies and cardiovascular disease-related anti-bacterial antibodies in pericardial fluid of cardiac surgery patients

D Simon, O Gilicze, N Farkas, J Najbauer… - Clinical & …, 2018 - academic.oup.com
… burgdorferi antibody titres. Our results provide the first evidence that natural autoantibodies
… significant correlation with certain anti-bacterial antibody titres in a disease-specific manner. …

Oxidized LDL antibodies in treatment and risk assessment of atherosclerosis and associated cardiovascular disease

J Nilsson, G Nordin Fredrikson… - Current …, 2007 - ingentaconnect.com
… The natural antibodies can be seen as a humoral equivalent of the cellular pattern … antibodies
that are found in complete absence of exogenous antigenic stimulation. Natural antibodies

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
… [Citation84] Anti-PC has traditionally been described as natural antibodies, which are germ
line encoded, and present from birth and where one clone, TI5 is dominant. This information …

Auto-antibodies as emergent prognostic markers and possible mediators of ischemic cardiovascular diseases

P Roux-Lombard, S Pagano, F Montecucco… - Clinical reviews in …, 2013 - Springer
Natural antibodies are defined as antibodies that … natural antibody T15 also bound to PC,
strongly suggesting that anti-PC, and, more generally, anti-oxLDL, are IgM natural antibodies

Evidence on the pathogenic role of auto-antibodies in acute cardiovascular diseases

F Carbone, A Nencioni, F Mach… - Thrombosis and …, 2013 - thieme-connect.com
… between some auto-antibodies and cardiovascular diseases (17). … prognostic value of
autoantibodies in cardiovascular patients. The … Natural antibodies with the T15 idiotype may act in …