… either the ligand (apelin −/− ) or the receptor (APJ −/− ) of this … apelin −/− and APJ −/− mice
have decreased basal cardiac … endogenous apelin-APJ signaling in basal contractile function …

… apelin–APJ system and explore its emerging pathogenetic significance and therapeutic
potential in cardiovascular … endogenous apelin–APJ signalling contributes to cardiac function. …

… and cardiovascular physiological actions of apelin/APJ system and … potential in several
major cardiovascular diseases. … for apelin/APJ system in maintaining basal cardiac function. …

… of tissues, mainly restricted to vascular endothelium. This … apelin and its role in cardiovascular
function and heart failure. … the function of the apelin-APJ system in the cardiovascular …

… Apelin–APJ signalling also attenuates ischemic myocardial injury and maintains cardiac …
Downregulation of apelin and APJ expression coincides with declining cardiac performance …

… ligand of APJ, reasonably explained … apelin/ELA-APJ system in cardiovascular physiology
and pathophysiology, as well as underlying mechanisms in development and cardiovascular …

… We review the literature regarding the apelin-APJ system in heart … function, 15 confirming
that the apelin-APJ system has a significant role in the maintenance of normal cardiac function. …

… recent apelin/APJ system research progress with emphasis on the influence of the system
on … For example, in the cardiovascular system, apelin/APJ could regulate vascular tone, …

… the effects of apelin on various aspects of the cardiovascular function, such as cardiac
development, … Taken together, these data indicate that the apelin/APJ system regulates cardiac …

… with apelin/APJ in cardiac hypertrophy and we elaborate the role of apelin/APJ in cardiac …
Within the cardiovascular system, apelin/APJ is able to induce peripheral and coronary …