Age-linked changes in the activity of enzymes of the tricarboxylate cycle and lipid oxidation, and of carnitine content, in muscles of the rat

RG Hansford, F Castro - Mechanisms of ageing and development, 1982 - Elsevier
content, as these parameters have been found to change in … , carnitine acetyltransferase
activity and carnitine content … a lower carnitine content and carnitine palmitoyltransferase activity

Age-dependent decrease of carnitine content in muscle of mice and humans

M Costell, JE O'Connor, S Grisolia - Biochemical and biophysical research …, 1989 - Elsevier
… are no reports on carnitine levels in healthy aging people. In this paper we show a marked
reduction of carnitine and its derivatives in muscle, and of long-chain acyl carnitine in heart of …

Long-term administration of L-carnitine to humans: effect on skeletal muscle carnitine content and physical performance

S Wächter, M Vogt, R Kreis, C Boesch, P Bigler… - Clinica Chimica …, 2002 - Elsevier
… for 4 weeks was associated with increased activities of mitochondrial enzymes, compatible …
The skeletal muscle fiber type composition did not change during the treatment with l-carnitine

The carnitine system and body composition

E Reda, S D'iddio, R Nicolai, P Benatti, M Calvani - Acta diabetologica, 2003 - Springer
… of genes resulting from carnitine system activities, which will … , a reduction in tissue lipid
content, and an increase in body … those related to carnitine-induced changes in molecular body …

Significance of lcarnitine for human health

MM Adeva‐Andany, I Calvo‐Castro… - IUBMB …, 2017 - Wiley Online Library
… l-carnitine content, but long-term l-carnitine supplementation … activity in these myotubes
leads to enhanced acetyl-carnitinechange in the distribution of plasma free l-carnitine and acyl-…

[HTML][HTML] Supplemental carnitine and exercise

EP Brass - The American journal of clinical nutrition, 2000 - Elsevier
… a significant change in muscle carnitine content will result from carnitine supplementation. …
decrease in muscle carnitine content and also increased muscle activity of key oxidative …

… reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart

LA Gómez, SHD Heath, TM Hagen - Mechanisms of ageing and …, 2012 - Elsevier
… Thus, assuming that there is no age-dependent change in CPT1 levels (a reasonable
assumption given no change in carnitine-supported kinetics), this analysis supports the concept …

Effect of l-Carnitine on Acetyl-CoA Content and Activity of Blood Platelets in Healthy and Diabetic Persons

A Michno, A Raszeja-Specht… - Clinical …, 2005 - academic.oup.com
… and cholinergic neuron activity in hyperglycemic states(6)(… carnitine changes the amounts
of acetyl-CoA in blood platelets and, if so, how it would affect basic indicators of platelet activity

Chronic oral ingestion of lcarnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans

BT Wall, FB Stephens… - The Journal of …, 2011 - Wiley Online Library
… , lactate, acetylcarnitine and free carnitine content changed by a similar magnitude during
… assistance with the determination of citrate synthase activity, QinetiQ for their sponsorship of …

Kinetics, pharmacokinetics, and regulation of l‐carnitine and acetyl‐l‐carnitine metabolism

CJ Rebouche - Annals of the New York Academy of Sciences, 2004 - Wiley Online Library
… acid-soluble carnitine content was not changed after 14 days of … changes in intracellular
l-carnitine concentration or changes in … changes in metabolic activity? Modest increases in tissue …