[HTML][HTML] Protective effect of carnosic acid, a pro-electrophilic compound, in models of oxidative stress and light-induced retinal degeneration

T Rezaie, SR McKercher, K Kosaka… - … & visual science, 2012 - iovs.arvojournals.org
… We have previously shown that carnosic acid (CA), present in rosemary extract, crosses the
blood–brain barrier to exert neuroprotective effects by upregulating endogenous antioxidant …

Protective effect of carnosic acid against acrylamide-induced toxicity in RPE cells

A Albalawi, RHA Alhasani, L Biswas, J Reilly… - Food and Chemical …, 2017 - Elsevier
protective effect of carnosic acid on acrylamide exposure, we assessed cell viability of ARPE-19
cells treated with carnosic acid … decreased when treated with carnosic acid of 40, 50 or …

[HTML][HTML] Neuroprotective effects of carnosic acid in an experimental model of Alzheimer's disease in rats

N Azad, H Rasoolijazi, MT Joghataie… - Cell Journal …, 2011 - ncbi.nlm.nih.gov
… The objective of the current investigation was to test the possibility that carnosic acid
could have a protective effect in a model of AD. For this purpose, the number of Nissle-stained …

Protective effect of rosmarinic acid and carnosic acid against streptozotocin-induced oxidation, glycation, inflammation and microbiota imbalance in diabetic rats

J Ou, J Huang, D Zhao, B Du, M Wang - Food & function, 2018 - pubs.rsc.org
… the protective effects of two rosemary components, rosmarinic acid (RA) and carnosic acid
(CA), … RA and CA also exhibited an anti-oxidative and anti-glycative effect by lowering the …

The dietary components carnosic acid and carnosol as neuroprotective agents: a mechanistic view

MR de Oliveira - Molecular neurobiology, 2016 - Springer
… Therefore, the aim of this work is to discuss about the protective effects exerted by CA and
carnosol, two dietary compounds, on neuronal and glial cells regarding its redox environment …

Neuroprotective effects of carnosic acid on neuronal cells under ischemic and hypoxic stress

CW Hou, YT Lin, YL Chen, YH Wang… - Nutritional …, 2012 - Taylor & Francis
Protective effects of antioxidants have been related with the preserved SOD and catalase
activities, lowering ROS, and preventing calcium release. Citation9,Citation17,Citation18 In …

Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

MR de Oliveira, GC Ferreira, PF Schuck… - Chemico-biological …, 2015 - Elsevier
Carnosic acid (CA), a phenolic diterpene isolated from Rosmarinus officinalis, exerts protective
effects in neuronal cells by increasing antioxidant defenses and detoxification systems. In …

Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats

C Kocak, FE Kocak, R Akcilar, OO Isiklar, H Kocak… - Life sciences, 2016 - Elsevier
… This is the first study to demonstrate the effect of EMB on Nrf2 in rats with ISO-induced
myocardial injury. Therefore, we suggest that the protective effects of EMB and CA in rats with …

Protective effect of carnosic acid against paraquat-induced redox impairment and mitochondrial dysfunction in SH-SY5Y cells: Role for PI3K/Akt/Nrf2 pathway

MR de Oliveira, GC Ferreira, PF Schuck - Toxicology in Vitro, 2016 - Elsevier
Carnosic acid (CA) is a phenolic diterpene isolated from Rosmarinus officinalis and exerts
… It has been reported that CA is able to cause protective effects on experimental models of …

[HTML][HTML] Protective effects of carnosic acid on lipopolysaccharide-induced acute kidney injury in mice

JY Kim, HL Hong, GM Kim, J Leem, HH Kwon - Molecules, 2021 - mdpi.com
… to determine whether carnosic acid has a therapeutic effect on LPS-… the effect of carnosic
acid on LPS-induced kidney injury. Our data demonstrated that administration of carnosic acid