[HTML][HTML] The effect of ageing and osteoarthritis on the mechanical properties of cartilage and bone in the human knee joint

AE Peters, R Akhtar, EJ Comerford, KT Bates - Scientific reports, 2018 - nature.com
… Osteoarthritis is traditionally associated with cartilagecartilage and bone material properties
during healthy ageing and … correlated cartilage, subchondral and trabecular bone samples (…

Aging bone and cartilage: cross-cutting issues

JL Carrington - Biochemical and biophysical research communications, 2005 - Elsevier
… the relationship between age-related changes in bone and cartilage and development of …
the decline in function of cartilage and bone. A better understanding of age-related changes in …

[PDF][PDF] Age variations in the properties of human tibial trabecular bone and cartilage

M Ding - Acta Orthopaedica Scandinavica, 2000 - Taylor & Francis
Age-related variations in the properties of trabecular bone and articular cartilage have …
There is an increase in the incidence of agerelated musculoskeletal diseases, such as osteo…

The age‐related changes in cartilage and osteoarthritis

YP Li, XC Wei, JM Zhou, L Wei - BioMed research international, 2013 - Wiley Online Library
… aging that exhibits increased nuclear DNA damage due to deficiency of a repair enzyme
found a significant increase in age-related bone loss but not in cartilage damage [87]. …

Ageing of human cartilage

D KApLAN, K Meyer - Nature, 1959 - nature.com
… -year-old had bone disease and mild diabetes secondary to Cooley's anremia. The rib
cartilage appears to be a tissue eminently suited for studies on ageing because it is less affected …

Effects of ageing on the biomechanical properties of rat articular cartilage

L Wang, DN Kalu, J Banu, JB Thomas… - Proceedings of the …, 2006 - journals.sagepub.com
… distal femoral articular cartilage as a function of age. Therefore… studying the age-related
changes of articular cartilage as they … the cartilage specimen automatically age-related bone loss …

The effect of aging and mechanical loading on the metabolism of articular cartilage

AEM Jørgensen, M Kjær, KM Heinemeier - The Journal of rheumatology, 2017 - jrheum.org
… Articular cartilage (AC) covers bone surfaces and allows for … in thickness or area in knee
cartilage 38 , while 10 weeks of … MRI of cartilage index in knee cartilage in women aged 20–…

Biochemistry of articular cartilage. Nature of proteoglycans and collagen of articular cartilage and their role in ageing and in osteoarthrosis.

CA McDevitt - Annals of the rheumatic diseases, 1973 - ncbi.nlm.nih.gov
cartilage which covers the articular surfaces of bones of vertebrate animals has two main
functions: the limitation of stress applied to the bone … functional demands the cartilage exhibits a …

Effects of aging on articular cartilage homeostasis

M Lotz, RF Loeser - Bone, 2012 - Elsevier
… It is possible that RAGE activation may play a more important role in OA as it develops in
older adults where, unlike in the young animals, AGE-formation in the cartilage would have had …

Cartilage regeneration and ageing: targeting cellular plasticity in osteoarthritis

M Varela-Eirin, J Loureiro, E Fonseca… - Ageing research …, 2018 - Elsevier
… secretome prevent age-related bone loss in mice by decreasing bone resorption and
improving bone formation (Farr et al., 2017). Further, senescence of muscle stem cells during …