A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure

Z Yu, J Coresh, G Qi, M Grams, E Boerwinkle… - Kidney international, 2020 - Elsevier
… In contrast, the causal effects of blood pressure on kidney function were not … causal effects
of higher kidney function on lower blood pressure and suggest preventing kidney function

Causal effects of physical activity or sedentary behaviors on kidney function: an integrated population-scale observational analysis and Mendelian randomization …

S Park, S Lee, Y Kim, Y Lee, MW Kang… - Nephrology Dialysis …, 2022 - academic.oup.com
causality of the effects of physical activity and specific sedentary activities on kidney function
… a sedentary lifestyle with the risk of kidney function impairment in an independent CKDGen …

[HTML][HTML] Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

AP Morris, TH Le, H Wu, A Akbarov… - Nature …, 2019 - nature.com
… the causal effects of eGFR on clinically-relevant renal and cardiovascular outcomes
through Mendelian randomisation (MR) with our expanded catalogue of kidney function loci. …

[HTML][HTML] Causal inference for the effect of environmental chemicals on chronic kidney disease

J Zhao, P Hinton, J Chen, J Jiang - Computational and structural …, 2020 - Elsevier
… Thus, in this study, the kidney function of participants was … causal relationship between
chemicals and kidney function, … examined the causal effect of PFA on renal function using a …

Causal effects from non‐alcoholic fatty liver disease on kidney function: a Mendelian randomization study

S Park, S Lee, Y Kim, S Cho, K Kim… - Liver …, 2022 - Wiley Online Library
… ) and kidney function impairment has been reported. We aimed to investigate the causal
effects … We hypothesized that causal effects of NAFLD on kidney function parameter, estimated …

[HTML][HTML] Mendelian randomization reveals causal effects of kidney function on various biochemical parameters

S Park, S Lee, Y Kim, S Cho, H Huh, K Kim… - Communications …, 2022 - nature.com
… As the effects from kidney function on diverse biochemical parameters are yet fully … the
causal effects is warranted. Here we show the causal estimates from kidney function parameter, …

[HTML][HTML] Causal effects of homocysteine, folate, and cobalamin on kidney function: a mendelian randomization study

S Park, S Lee, Y Kim, S Cho, K Kim, YC Kim, SS Han… - Nutrients, 2021 - mdpi.com
… We aimed to assess causal effects of blood homocysteine, folate, and cobalamin on kidney
function in the general population by performing Mendelian randomization (MR) analysis. …

The causal effects of serum lipids and apolipoproteins on kidney function: multivariable and bidirectional Mendelian-randomization analyses

H Rasheed, J Zheng, J Rees… - International Journal …, 2021 - academic.oup.com
… using data from general-population cohorts in which most participants had normal kidney
function, so our results reflect associations within the healthy range of kidney function. …

[HTML][HTML] The causal effects of lipid traits on kidney function in Africans: bidirectional and multivariable Mendelian-randomization study

C Kintu, O Soremekun, AB Kamiza, A Kalungi… - …, 2023 - thelancet.com
causal association between lipid traits and kidney function in continental Africans. However,
due to the unexpected causal … true causality between serum lipids and kidney function. We …

Causal effects of education on chronic kidney disease: a Mendelian randomization study

S Park, S Lee, Y Kim, Y Lee, MW Kang… - Clinical Kidney …, 2021 - academic.oup.com
… The CKDGen Consortium performed the largest currently available genome-wide association
meta-analysis of kidney function outcomes. We utilized the summary statistics for CKD …