[HTML][HTML] CC chemokines in idiopathic pulmonary fibrosis: pathogenic role and therapeutic potential

S Liu, C Liu, Q Wang, S Liu, J Min - Biomolecules, 2023 - mdpi.com
… Here, we review the roles of different CC chemokines in the pathogenesis of IPF, and their
… of CC chemokines and CXC chemokines in lung tissues, suggesting that these chemokines

The role of the Th2 CC chemokine ligand CCL17 in pulmonary fibrosis

JA Belperio, M Dy, L Murray, MD Burdick… - The Journal of …, 2004 - journals.aai.org
… of pulmonary fibrosis is a Th2-mediated process. We hypothesized that the CC chemokines
… important role in the development of pulmonary fibrosis. We measured CCL17 and CCL22 …

CCR5 expression and CC chemokine levels in idiopathic pulmonary fibrosis

A Capelli, A Di Stefano, I Gnemmi… - European Respiratory …, 2005 - Eur Respiratory Soc
… the involvement of CC chemokines and the expression of CCR5 in idiopathic pulmonary
fibrosis (IPF) and, … CC chemokine ligand (CCL)2, CCL3 and CCL4 levels were measured in the …

Essential roles of the CC chemokine ligand 3-CC chemokine receptor 5 axis in bleomycin-induced pulmonary fibrosis through regulation of macrophage and fibrocyte …

Y Ishida, A Kimura, T Kondo, T Hayashi, M Ueno… - The American journal of …, 2007 - Elsevier
… We investigated the pathogenic roles of CC chemokine ligand (CCL)3 and its receptors, CC
chemokine receptor (CCR)1 and CCR5, in bleomycin (BLM)-induced pulmonary fibrosis (PF)…

A role for CC chemokines in fibrotic lung disease

RE Smith, RM Stricter, K Zhang, SH Phan… - Journal of Leucocyte …, 1995 - academic.oup.com
Pulmonary fibrosis is the end point of a chronic inflammatory process characterized by …
models of pulmonary fibrosis have investigated the role of cytokines in the evolution of the fibrotic

Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis

C Agostini, C Gurrieri - Proceedings of the American Thoracic …, 2006 - atsjournals.org
… However, there are data indicating the relative contribution in lung fibrosis of members of
the CC chemokine family, such as monocyte chemotactic protein-1 (MCP-1/CCL2), …

CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosis

M Gharaee-Kermani, RE McCullumsmith, IF Charo… - Cytokine, 2003 - Elsevier
… MCP-1, which signals via the CC chemokine receptor 2 (CCR2), is induced in lung fibrosis
fibrosis, CCR2 knockout (ko) mice were used in a model of bleomycin-induced lung fibrosis. …

[HTML][HTML] The role of CXC chemokines in pulmonary fibrosis

RM Strieter, BN Gomperts… - The Journal of clinical …, 2007 - Am Soc Clin Investig
… Therefore, through the induction of IFN-γ, Th1 cytokines such as IL-2, IL-12, IL-15, IL-18,
and IL-23 and chemokines such as CC chemokine ligand 19 (CCL19) and CCL21 have …

CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab

G Raghu, FJ Martinez, KK Brown… - European …, 2015 - Eur Respiratory Soc
The objective of this study was to determine the safety and efficacy of carlumab in the
treatment of idiopathic pulmonary fibrosis (IPF). A phase 2, randomised, double-blind placebo-…

[HTML][HTML] C (C) Learing the role of chemokines in pulmonary fibrosis

C He, AB Carter - American Journal of Respiratory Cell and …, 2020 - atsjournals.org
… Important roles for macrophage colony-stimulating factor, CC chemokine ligand 2, and
mononuclear phagocytes in the pathogenesis of pulmonary fibrosis. Am J Respir Crit Care Med …