CCR2 expression on circulating monocytes is associated with arterial wall inflammation assessed by 18F-FDG PET/CT in patients at risk for cardiovascular disease

SL Verweij, R Duivenvoorden… - Cardiovascular …, 2018 - academic.oup.com
wall inflammation. We hypothesized that the expression levels of chemokine receptors (CCR2
, CD11c) on circulating monocytes correlated with the extent of arterial wall inflammation. …

Expression of CCR2 by endothelial cells: implications for MCP-1 mediated wound injury repair and in vivo inflammatory activation of endothelium

KSC Weber, PJ Nelson, HJ Gröne… - … , and vascular biology, 1999 - Am Heart Assoc
… of endothelial CCR2 by inflammatory cytokines, which induce endothelial secretion of
MCP-1, may promote endothelial migration under conditions such as inflammatory reactions or …

Induction of CCR2‐dependent macrophage accumulation by oxidized phospholipids in the air‐pouch model of inflammation

A Kadl, E Galkina, N Leitinger - Arthritis & Rheumatism, 2009 - Wiley Online Library
… the expression of a set of chemokines in the air-pouch wall, … We conclude that down-regulation
of CCR2 expression on … the prolonged arrest of inflammatory macrophages in damaged …

Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling

M Ishibashi, K Hiasa, Q Zhao, S Inoue… - Circulation …, 2004 - Am Heart Assoc
… that CCR2 expression in monocytes has a critical role in vascular inflammation and … To
dissect the relative pathobiological role of monocytes versus nonmonocyte cells in the arterial wall

Crucial role of the CCL2/CCR2 axis in neointimal hyperplasia after arterial injury in hyperlipidemic mice involves early monocyte recruitment and CCL2 presentation …

A Schober, A Zernecke, EA Liehn… - Circulation …, 2004 - Am Heart Assoc
… chemokine receptor 2 (CCR2) play a central role in the inflammatory response and neointimal
… , locally expressed CCL2 can recruit monocytes into the vessel wall via CCR2. Because …

[HTML][HTML] Salt increases monocyte CCR2 expression and inflammatory responses in humans

EFE Wenstedt, SGS Verberk, J Kroon, AE Neele… - JCI insight, 2019 - ncbi.nlm.nih.gov
expression of CCR2, a chemokine receptor that mediates monocyte infiltration in inflammatory
… increased HLA-DR expression and decreased CD206 expression on skin macrophages …

CCL2-CCR2 signaling in disease pathogenesis

T O'Connor, L Borsig… - Endocrine, Metabolic & …, 2015 - ingentaconnect.com
… of CCR2-expressing inflammatory monocytes from the circulation into the brain parenchyma.
… Atherosclerosis is the thickening of arterial walls and the formation of obstructive plaques …

CCR2 positron emission tomography for the assessment of abdominal aortic aneurysm inflammation and rupture prediction

SJ English, SE Sastriques, L Detering… - Circulation …, 2020 - Am Heart Assoc
… biomarkers expressed on monocytes/macrophages, CCR2 (… to the site of inflammation in
the arterial wall following injury. A … In the current study, elevated CCR2 expression in AAAs led …

The CCR2 receptor as a therapeutic target

M Feria, F Díaz-González - Expert Opinion on Therapeutic Patents, 2006 - Taylor & Francis
… MS is the most common inflammatory demyelinating disease of the human CNS. Although
… CCL2 and CCR2 in the recruitment of inflammatory cells in the CNS. CCL2 expression in the …

Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus

TC Dawson, MA Beck, WA Kuziel, F Henderson… - The American journal of …, 2000 - Elsevier
expression of a number of CC chemokines. CC chemokine receptors CCR5 and CCR2 are
both expressed … and tissue consolidation, thickening of the septal walls, and disorganization …