Developments in CD4 and viral load monitoring in resource-limited settings

CF Rowley - Clinical infectious diseases, 2014 - academic.oup.com
CD4 count and human immunodeficiency virus (HIV) load tests have long been a part of the
routine monitoring of … on the importance of monitoring CD4 count and viral load in resource-…

The future role of CD4 cell count for monitoring antiretroviral therapy

N Ford, G Meintjes, A Pozniak, H Bygrave… - The Lancet Infectious …, 2015 - thelancet.com
… The second study followed 141 stable patients with viral loads less than 50 copies/mL on
ART and CD4 count 350 cells per μL or greater for a median of 2·5 years: only 13 patients (9%) …

CD4 cell count and viral load monitoring in patients undergoing antiretroviral therapy in Uganda: cost effectiveness study

JG Kahn, E Marseille, D Moore, R Bunnell, W Were… - Bmj, 2011 - bmj.com
… adjusted life years (DALYs) averted), and cost per DALY averted of adding CD4 counts to
clinical monitoring and of adding viral load testing to CD4 counts and clinical monitoring. …

Utility of routine viral load, CD4 cell count, and clinical monitoring among adults with HIV receiving antiretroviral therapy in Uganda: randomised trial

J Mermin, JP Ekwaru, W Were, R Degerman, R Bunnell… - Bmj, 2011 - bmj.com
… routine viral loads or CD4 counts, or both, received these results on a quarterly basis. …
the efficacy of both routine CD4 cell count and viral load monitoring on clinical outcomes in a …

Monitoring of HIV viral load, CD4 cell count, and clinical assessment versus clinical monitoring alone for antiretroviral therapy in low-resource settings (Stratall ANRS …

S Boyer, L March, C Kouanfack… - The Lancet infectious …, 2013 - thelancet.com
… A combined strategy in which LAB would only be used in patients starting ART with a
CD4 count of 200 cells per μL or fewer suggests that 0·120 life-years would be saved at an …

CD4 counting technologies for HIV therapy monitoring in resource-poor settings–state-of-the-art and emerging microtechnologies

MT Glynn, DJ Kinahan, J Ducrée - Lab on a Chip, 2013 - pubs.rsc.org
… use a CD4 count to determine if a patient should begin ART, and also to monitor the recovery
… is the measurement of HIV viral load in a patient, but this review will focus only on CD4 cell …

Monitoring of HIV viral loads, CD4 cell counts, and clinical assessments versus clinical monitoring alone for antiretroviral therapy in rural district hospitals in Cameroon …

C Laurent, C Kouanfack, G Laborde-Balen… - The Lancet infectious …, 2011 - thelancet.com
… We randomly assigned participants (1:1) to CLIN or LAB (counts of HIV viral load and CD4
The primary outcome was non-inferiority of CLIN to LAB in terms of increase in CD4 cell count

Outcomes from monitoring of patients on antiretroviral therapy in resource-limited settings with viral load, CD4 cell count, or clinical observation alone: a computer …

AN Phillips, D Pillay, AH Miners, DE Bennett, CF Gilks… - The Lancet, 2008 - thelancet.com
… with use of viral load monitoring. We found little suggestion that monitoring of CD4 cell counts
results in improved survival compared with clinical monitoring. Although we focused on a …

CD 4 count‐based failure criteria combined with viral load monitoring may trigger worse switch decisions than viral load monitoring alone

CJ Hoffmann, J Maritz… - Tropical Medicine & …, 2016 - Wiley Online Library
… Our data suggest that CD4 count monitoring may lead to inappropriate delayed therapy …
a CD4 count decline and thus may be more likely to be switched to a second-line regimen. …

Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count …

D Meya, LA Spacek, H Tibenderana, L John… - Journal of the …, 2009 - Springer
… -certified laboratory and is able to perform CD4 cell counts and viral load testing on site. …
from on-treatment peak value; and WHO immunologic failure criteria (fall of CD4 count to pre-…