Effect of Chronic Oxidative Stress on Neuroinflammatory Response Mediated by CD4+T Cells in Neurodegenerative Diseases

H Solleiro-Villavicencio… - Frontiers in cellular …, 2018 - frontiersin.org
… ROS on microglia, astrocytes, and CD4 + T cells. Furthermore, we will describe the role that
CD4 + T cell subpopulations play in some of the most important neurodegenerative diseases

T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases

H González, R Pacheco - Journal of neuroinflammation, 2014 - Springer
… In this review, we focus on the analysis of the interplay of the different sub-populations of
CD4 + T-cells infiltrating the CNS and how they participate in regulating the outcome of …

CD4+ T cells mediate cytotoxicity in neurodegenerative diseases

SH Appel - The Journal of clinical investigation, 2009 - Am Soc Clin Investig
… Here we showed that CD8+ and CD4+ T cells but not B cells had invaded the brain in both
… dopaminergic cell death was markedly attenuated in the absence of mature T lymphocytes in …

The role of regulatory T cells in neurodegenerative diseases

F He, R Balling - Wiley Interdisciplinary Reviews: Systems …, 2013 - Wiley Online Library
neurodegenerative diseases. Interestingly, a dysfunction of Tregs is mainly observed in the
early stages of several neurodegenerative diseases… in CD4 + T cells, conclusions about CD4

CD 4+ T cells in the pathobiology of neurodegenerative disorders

X Huang, AD Reynolds, RL Mosley… - Journal of …, 2009 - Elsevier
… of adaptive immunity for neurodegenerative diseases. Particularly, we will outline how and
under what conditions CD4+ T cells could elicit … Neurodegenerative disorders and immunity …

T cells: a growing universe of roles in neurodegenerative diseases

D Dressman, W Elyaman - The Neuroscientist, 2022 - journals.sagepub.com
… of T cells in neurodegenerative diseases. We summarize the subsets of T cells, their …
CD4+ T cells are divided into different subsets based on their developmental program, their …

The Trojan horse-neuroinflammatory impact of T cells in neurodegenerative diseases

A Sommer, B Winner, I Prots - Molecular neurodegeneration, 2017 - Springer
… of CD4 + T cells [12] and reduced CD4 + : CD8 + T cell ratios … -driven neurodegenerative
disease MS, T lymphocyte … Reduction of both, total CD3 + and CD4 + T cells were found …

Regulation of the neurodegenerative process associated to Parkinson's disease by CD4+ T-cells

H González, F Contreras, R Pacheco - Journal of Neuroimmune …, 2015 - Springer
CD4+ T-cells in the healthy brain, inflammatory CD4+ T-cells … associated to neurodegenerative
diseases such as PD, AD, MS … associated to neurodegenerative diseases would result in …

The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases

A DeMaio, S Mehrotra, K Sambamurti… - Journal of …, 2022 - Springer
… However, T cell involvement and the disruption of the blood–… neurodegenerative diseases
including Parkinson's disease, … subsets of CD4 + cells [63], but now CD4 + T cells have been …

CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson's disease

GP Williams, AM Schonhoff, A Jurkuvenaite… - Brain, 2021 - academic.oup.com
CD4 T cells in Parkinson’s disease neurodegeneration. It is important to note that although
this study mainly implicates a CD4 T cell role in Parkinson’s disease, the CD8 T cell … s disease