Differential CD40/CD40L expression results in counteracting antitumor immune responses
G Murugaiyan, R Agrawal, GC Mishra… - The Journal of …, 2007 - journals.aai.org
… an immune response. The nature of antitumor immune response is a function of the extent of
CD40 … have important implications for the immunotherapy of infectious diseases and cancer. …
CD40 … have important implications for the immunotherapy of infectious diseases and cancer. …
Mechanistic basis of co-stimulatory CD40-CD40L ligation mediated regulation of immune responses in cancer and autoimmune disorders
… of the CD40 with a deregulated amount of CD40 ligand has been implicated … CD40-CD40L
mediated regulation of immune response and involvement in the pathophysiology of cancer …
mediated regulation of immune response and involvement in the pathophysiology of cancer …
Molecular mechanism and function of CD40/CD40L engagement in the immune system
R Elgueta, MJ Benson, VC De Vries… - Immunological …, 2009 - Wiley Online Library
… immune response, abrogation of the CD40/CD40L pathway has no impact on the thymus-independent
(TI) antibody response… anti-tumor immunity and CD40 can be a cancer-associated …
(TI) antibody response… anti-tumor immunity and CD40 can be a cancer-associated …
Role for CD40–CD40 ligand interactions in the immune response to solid tumours
AB Alexandroff, AM Jackson, T Paterson, JL Haley… - Molecular …, 2000 - Elsevier
… immune cells. In the current study we examined the role of CD40-mediated interactions in
immune responses … Finally, the presence of CD40 on the surface of carcinoma lines was found …
immune responses … Finally, the presence of CD40 on the surface of carcinoma lines was found …
[HTML][HTML] CD40/CD40 ligand interactions in immune responses and pulmonary immunity
T Kawabe, M Matsushima, N Hashimoto… - Nagoya journal of …, 2011 - ncbi.nlm.nih.gov
… on the role of the CD40L/CD40 costimulatory system in the context of … of the CD40L/CD40
system can be found in the literature. … We established CD40L-expressing lung cancer cells by …
system can be found in the literature. … We established CD40L-expressing lung cancer cells by …
The role of the CD40 pathway in the pathogenesis and treatment of cancer
AG Eliopoulos, LS Young - Current opinion in pharmacology, 2004 - Elsevier
… Indeed, the activation of CD40 by CD40 ligand (CD40L) … immune responses, promoting
their differentiation into immunoglobulin-producing plasma cells. In addition, the CD40-CD40L …
their differentiation into immunoglobulin-producing plasma cells. In addition, the CD40-CD40L …
Multiple effects of CD40–CD40L axis in immunity against infection and cancer
… Citation15 CD40–CD40L is a pair of costimulatory … immune responses. There is a plethora
of reports that suggest the importance of CD40–CD40L interaction in immune responses …
of reports that suggest the importance of CD40–CD40L interaction in immune responses …
Use of CD40L immunoconjugates to overcome the defective immune response to vaccines for infections and cancer in the aged
YC Tang, M Thoman, PJ Linton… - Cancer Immunology …, 2009 - Springer
… to the target antigen, as the carboxylterminus of CD40L is the end of CD40L, which
engages the CD40 receptor. Since all of the sequences necessary for the assembly of the …
engages the CD40 receptor. Since all of the sequences necessary for the assembly of the …
The CD40/CD40L system: a new therapeutic target for disease
B Zhang, T Wu, M Chen, Y Zhou, D Yi, R Guo - Immunology letters, 2013 - Elsevier
… as atherosclerosis, diabetes mellitus, immunological rejection and cancer. … CD40/CD40L
system as applied to a range of cardiovascular diseases, immune system disorders and cancers…
system as applied to a range of cardiovascular diseases, immune system disorders and cancers…
CD40 ligand induces an antileukemia immune response in vivo
D Dilloo, M Brown, M Roskrow, W Zhong… - Blood, The Journal …, 1997 - ashpublications.org
… CD40L could enhance an antileukemia immune response using a CD40 + murine lymphoblastic
(A20) leukemia and a CD40 − … presence of CD40L induced an immune response active …
(A20) leukemia and a CD40 − … presence of CD40L induced an immune response active …
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