… CD8 T cells for long-term response is well established [28, 29]. However, the mechanisms by
which T-bet facilitates transition of type 1 effector CD8 T cells … cell fate in CD8 T cells, since …

… adopt the CD8 lineage instead. This suggests that Notch activity normally acts to direct
CD4 + CD8 + precursors to the CD8 lineage. The choice between CD4 and CD8 T cell fates is …

… The extent of Lck activation was proposed to control cell fate 31 ; TCR–co-receptor crosslinking
produced CD4 + SP T cells because this provided more Lck input than TCR crosslinking …

… In this report, we used a novel approach to fate map CD8+ T cells produced during
different stages of life, allowing the identification of developmental layers in the CD8+ T cell …

… This review focuses on CD8 T cell immunity directed towards foreign antigens expressed in
… intrahepatic CD8 T cell responses. Potential strategies to rescue unresponsive CD8 T cells …

… how heterogeneity in antiviral T cell populations gives rise to T cell subsets with short- and
long-lived cell fates. … Molecular and functional profiling of memory CD8 T cell differentiation. …

… the tight linkage between CD8 versus CD4 T cell fate and the … for the CD4 versus CD8 T
cell fate decision that reflects the … regulation of CD4 and CD8 T cell fate, we refer the reader to …

… were gained through in vivo fate mapping of single T cells and discuss how these … T cell
fate diversification and memory T cell ontogeny. One Cell, One Fate or One Cell, Multiple Fates …

… -regulated late in effector but not central CD8 T cells. Thus, our data suggest that cell fate
determination in memory CD8 T cells operates according to an expression gradient of specific …

… The initiation of the T cell exhaustion … ) CD8 T cell binary-fate decision during chronic
infection and find that TCF-1 supports the Tex precursor development by antagonizing Teff-like cell …