Virus‐specific CD8 T cells: activation, differentiation and memory formation
M Wiesel, S Walton, K Richter, A Oxenius - Apmis, 2009 - Wiley Online Library
… duration and strength of CD8 T cell stimulation, the … T cell help and CD8 T cell precursor
frequencies. With respect to the timing when CD8 T cells are committed to become memory cells…
frequencies. With respect to the timing when CD8 T cells are committed to become memory cells…
Plasticity in programming of effector and memory CD8+ T‐cell formation
R Arens, SP Schoenberger - Immunological reviews, 2010 - Wiley Online Library
… Optimal clonal expansion and memory formation but not the functionality of effector CD8
+ T cells is however achieved when antigenic stimulation is prolonged to 2–4 days (46, 103), …
+ T cells is however achieved when antigenic stimulation is prolonged to 2–4 days (46, 103), …
The multifaceted role of CD4+ T cells in CD8+ T cell memory
… + T cells act to support memory CD8 + T cell development … role of CD4 + T cells in the
regulation of memory CD8 + T cell … which T Reg cells can regulate memory formation following …
regulation of memory CD8 + T cell … which T Reg cells can regulate memory formation following …
Understanding memory CD8+ T cells
T Samji, KM Khanna - Immunology letters, 2017 - Elsevier
… Here we discuss the most current understanding of different subsets of memory CD8 T cells
and their … factors that are important for the formation of MPECs and memory CD8 + T cells. …
and their … factors that are important for the formation of MPECs and memory CD8 + T cells. …
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
GA Kolumam, S Thomas, LJ Thompson… - The Journal of …, 2005 - rupress.org
… -IR 0 ) and –sufficient CD8 T cells adoptively transferred into normal IFN-IR … CD8 T cell
contact with IFN-I causes >99% reduction in their capacity to expand and generate memory cells…
contact with IFN-I causes >99% reduction in their capacity to expand and generate memory cells…
Defining memory CD8 T cell
MD Martin, VP Badovinac - Frontiers in immunology, 2018 - frontiersin.org
… Of note, displaying the expression pattern of markers used to identify SLECs (CD127 − /KLRG1
+ ) does not absolutely preclude long-term memory formation, as a small percentage of …
+ ) does not absolutely preclude long-term memory formation, as a small percentage of …
Extent of stimulation controls the formation of memory CD8 T cells
M Quigley, X Huang, Y Yang - The Journal of Immunology, 2007 - journals.aai.org
… diminished survival of activated CD8 T cells in vitro and defective CD8 memory formation in
vivo. … CD8 T cells are short-lived or develop into long-term memory cells via activation of Akt. …
vivo. … CD8 T cells are short-lived or develop into long-term memory cells via activation of Akt. …
Developing and maintaining protective CD8+ memory T cells
MA Williams, BJ Holmes, JC Sun… - Immunological …, 2006 - Wiley Online Library
… Rather, CD8 + memory cells formed and maintained in the absence of CD4 + help were
specifically defective in their ability to expand and protect following secondary infection, as …
specifically defective in their ability to expand and protect following secondary infection, as …
Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation
… the transcriptional regulation that influence memory formation and CD8 + T cell immunity. …
specifically in the function of memory and late memory CD8 + T cells, we looked for transcripts …
specifically in the function of memory and late memory CD8 + T cells, we looked for transcripts …
Autophagy is essential for effector CD8+ T cell survival and memory formation
… for CD8 + T cell memory generation To determine the importance of the increase in autophagy
activity during the transition phase from effector CD8 + T cells to memory CD8 + T cells, …
activity during the transition phase from effector CD8 + T cells to memory CD8 + T cells, …
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