[HTML][HTML] CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses

KE Lineburg, EJ Grant, S Swaminathan… - Immunity, 2021 - cell.com
T cell receptor (TCR) sequencing indicated that cross-reactivity was driven by private TCR
… basis of selective T cell cross-reactivity for an immunodominant SARS-CoV-2 epitope and its …

[HTML][HTML] CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity

THO Nguyen, LC Rowntree, J Petersen, BY Chua… - Immunity, 2021 - cell.com
… -2)-specific T cells. By … CD8 + T cells specific for SARS-CoV-2 epitopes in COVID-19 patients
and unexposed individuals. Unlike CD8 + T cells directed toward subdominant epitopes (B7…

Identification of SARS-CoV-2 nucleocapsid and spike T-cell epitopes for assessing T-cell immunity

E Lee, K Sandgren, G Duette, VV Stylianou… - Journal of …, 2021 - Am Soc Microbiol
… B cell epitopes predicted by BepiPred Linear Epitope prediction 2.0. The consecutive
amino acid residues within the B cell epitopes that are identical to the T-cell epitope derived …

Overlapping CD8+ and CD4+ T-cell epitopes identification for the progression of epitope-based peptide vaccine from nucleocapsid and glycoprotein of emerging Rift …

UK Adhikari, MM Rahman - Infection, Genetics and Evolution, 2017 - Elsevier
CD8 + T-cell epitopes; whereas two epitopes were overlapping with decamer linear B-cell
epitopes and the rest of the other eleven epitopes (1 … CD4 + T-cell epitopes (peptides). On the …

[HTML][HTML] SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell …

…, J Ciffelo, R Yin, J McKelvy, D Melvin, T Wallace… - Nature …, 2023 - nature.com
… observe the expansion of CD8 + T cells specific to these six nucleocapsid epitopes (Fig. 3a)…
all six nucleocapsid epitopes, while uninfected donors could only respond to four epitopes (…

[HTML][HTML] An effective CTL peptide vaccine for Ebola Zaire Based on Survivors' CD8+ targeting of a particular nucleocapsid protein epitope with potential implications …

…, J Sidney, A Sette, PE Harris, S Massey, T Brasel… - Vaccine, 2020 - Elsevier
… on Survivors’ CD8+ targeting of a particular nucleocapsid protein epitope with potential
implications … Vaccine-elicited human t cells recognizing conserved protein regions inhibit hiv-1 …

[HTML][HTML] Dominant CD8+ T Cell Nucleocapsid Targeting in SARS-CoV-2 Infection and Broad Spike Targeting From Vaccination

E Taus, C Hofmann, FJ Ibarrondo, MA Hausner… - Frontiers in …, 2022 - frontiersin.org
… The sets of predicted CD4 + T cell epitopes and overlapping spike peptides were combined
in one pool, and the two sets of predicted CD8 + T cell epitopes were combined in a second …

Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen.

…, G Missale, M Pilli, P Fowler, T Giuberti… - The Journal of …, 1991 - Am Soc Clin Investig
… In conclusion, the identification of immunodominant T cell epitopes within the core molecule
T cellspolyclonal T cell lines * acute hepatitis - hepatitis B vaccine Introduction The cell-…

Hantavirus pulmonary syndrome: CD8+ and CD4+ cytotoxic T lymphocytes to epitopes on Sin Nombre virus nucleocapsid protein isolated during acute illness

FA Ennis, J Cruz, CF Spiropoulou, D Waite, CJ Peters… - Virology, 1997 - Elsevier
… In conclusion, CD8/ and CD4/ CTL epitopes on SNV these cytokines could cause the …
nucleocapsid protein have been identified using CD8/ and CD4/ clones that were isolated from the …

Human CD4+ T cells specific for dominant epitopes of SARS-CoV-2 Spike and Nucleocapsid proteins with therapeutic potential

J Verhagen, ED van Der Meijden, V Lang… - Clinical & …, 2021 - academic.oup.com
… + T cells specific for immunodominant epitopes from Spike and Nucleocapsid proteins. These
… Here, we describe the identification of CD4+ T cells specific for immunodominant epitopes