… CEBPA-dm. This study validates our previous observation on the favorable impact of CEBPA-bZip
… clinical outcome data for cooperating mutations in patients with CEBPA-mutant AML. …

… We are speculating that this function acquired by the CEBPA bZIP mutant determines the …
in bZIP is strongly associated with a favorable prognosis, whereas CEBPAmu out-of bZIP is …

… CEBPA bZIP-inf and CEBPA other (including CEBPA smTAD and non-CEBPA bZIP-inf ), only
patients bearing CEBPA bZIP-… previously undefined prognostic role of this type of mutation. …

… CEBPA mutations and the significance of bZIP in-f CEBPA. To clarify the prognostic significance
of bZIP in-f CEBPA in AML, we directly compared the treatment results according to the …

… In cases where both bZIP in-f CEBPA and FLT3-ITD coexist, … prognostic significance is
limited. Therefore, we aimed to evaluate the prognostic significances of the co-occurrence of bZIP …

… limited to cases with double CEBPA mutations and not … CEBPA mutation is associated with
good overall survival and event-free survival, with particular relevance to those within the bZip …

… occurred in the bZip domain, had similar outcomes to CEBPA-dm … with CEBPA mutations.
In this large analysis, we sought to define the prognostic impact of CEBPA-dm vs single bZip …

… bZIP domain of CEBPA (CEBPA bZIP-inf ) define a distinct entity associated with favorable
prognosis … CEBPA mutations could activate the BCL2 P2 promoter and induce its expression …

… the CEBPA bZIP InDel genotype introduced in this work (bZIP in-… favorable prognostic
implications, whereas the other CEBPA mutational subgroups, ie TAD mutations as well as bZIP …

… In conclusion, although CEBPA bZIP mutations affect only a small subgroup of all … CEBPA
bZIP mutations are strong independent predictors for the achievement of CR and favourable …