Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group

PA Ho, TA Alonzo, RB Gerbing, J Pollard… - Blood, The Journal …, 2009 - ashpublications.org
… We evaluated the prevalence and prognostic significance of CEBPA mutations in 847 … types
of CEBPA mutations—N-terminal truncating mutations and in-frame bZip-domain mutations—…

[引用][C] Genetic Changes of CEBPA in Cancer: Mutations or Polymorphisms?

C Resende, G Regalo, C Durães, F Carneiro… - … of clinical oncology, 2007 - ascopubs.org
… cells,7 we sought to establish if CEBPA mutations identified in AML could also be present
in … coding region of CEBPA in 142 patients with gastric carcinoma. Mutation screening was …

CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome

F Taube, JA Georgi, M Kramer, S Stasik… - Blood, The Journal …, 2022 - ashpublications.org
… However, the impact of monoallelic CEBPA mutations has been … mutations. To investigate
the prevalence and prognostic role of CEBPA mutations, in particular CEBPA sm mutations, in …

Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA

NP Konstandin, F Pastore, T Herold, A Dufour… - Blood …, 2018 - ashpublications.org
CEBPA mutations can be either biallelic or monoallelic. Most patients with 2 CEBPA mutations
carry 1 frameshift mutation … A single CEBPA mutation is most often found at the N terminus…

CEBPA-bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children's Oncology Group

K Tarlock, AJ Lamble, YC Wang… - Blood, The Journal …, 2021 - ashpublications.org
CEBPA-basic leucine zipper (CEBPA-bZip) mutations in children and young adults with
newly diagnosed AML. CEBPA-bZip mutation … Children’s Oncology Group trials (NCT00003790, …

CEBPA Mutations in Younger Adults With Acute Myeloid Leukemia and Normal Cytogenetics: Prognostic Relevance and Analysis of Cooperating Mutations

S Fröhling, RF Schlenk, I Stolze, J Bihlmayr… - … of Clinical Oncology, 2004 - ascopubs.org
… the prognostic relevance of CEBPA mutations in a homogeneous group of young adults …
protocols of the AML Study Group Ulm. In a search for cooperating mutations and to provide a …

… genetic mutations, and gene expression features of AML with CEBPA mutations in a cohort of 1182 cytogenetically normal AML patients: further evidence for CEBPA …

E Taskesen, L Bullinger, A Corbacioglu… - Blood, The Journal …, 2011 - ashpublications.org
… For these purposes, we combined datasets from the Dutch-Belgian Hemato-Oncology
Cooperative Group (HOVON)-Swiss Group for Clinical Cancer Research (SAKK) and the German …

Prognostic significance of CEBPA mutations in a large cohort of younger adult patients with acute myeloid leukemia: impact of double CEBPA mutations and the …

CL Green, KK Koo, RK Hills, AK Burnett… - … of Clinical Oncology, 2010 - ascopubs.org
mutations have also been described. Recent data have suggested that the good prognosis
may be limited to double, not single, CEBPA … of CEBPA mutations, we investigated mutation

Acute Myeloid Leukemia With Biallelic CEBPA Gene Mutations and Normal Karyotype Represents a Distinct Genetic Entity Associated With a Favorable Clinical …

A Dufour, F Schneider, KH Metzeler… - … of clinical oncology, 2010 - ascopubs.org
CEBPA mutations are found as either biallelic (biCEBPA) or … We set out to explore whether
the kind of CEBPA mutation is … two CEBPA mutations, the distribution of the mutations was …

Long-term follow-up of cytogenetically normal CEBPA-mutated AML

F Pastore, D Kling, E Hoster, A Dufour… - … Hematology & Oncology, 2014 - Springer
… of material, we cannot confirm the presence of a CEBPA mutation at relapse. Both cases
underline the importance of a long-term follow-up of patients with AML and CEBPA mutations. …