The structure of the T cell antigen receptor
GA Bentley, RA Mariuzza - Annual review of immunology, 1996 - annualreviews.org
… tyrosine kinase receptors(87). There is considerable evidencethat antigen receptors, both
… long beenknown that T cells can be triggered by divalent antibodies specific for TCR orCD3 …
… long beenknown that T cells can be triggered by divalent antibodies specific for TCR orCD3 …
On the structure of the T-cell receptor for antigen
U Krawinkel, M Cramer, C Berek… - Cold Spring Harbor …, 1977 - symposium.cshlp.org
… the functional antigen receptor of T helper cells. The … structure of lymphocyte surface receptors
for antigen directly, we developed a method which permits the specific isolation of antigen-…
for antigen directly, we developed a method which permits the specific isolation of antigen-…
[PDF][PDF] Structure, func-tion, and serology of the T cell antigen receptor com-plex
JP Allison, LL Lanier - Ann. Rev. Immunol, 1987 - researchgate.net
… antibodies are practically all specific for the cells … structure and function of the antigen
receptor--to be discussed later. Second, the antibodies specifically precipitated similar structures. …
receptor--to be discussed later. Second, the antibodies specifically precipitated similar structures. …
Predicted complementarity determining regions of the T cell antigen receptor determine antigen specificity.
CD Katayama, FJ Eidelman, A Duncan… - The EMBO …, 1995 - embopress.org
… , we sought to determine whether the antigen specificity of the TCR could … receptor were
important. In addition, if other parts of the receptor structure were important to peptide specificity, …
important. In addition, if other parts of the receptor structure were important to peptide specificity, …
T cell antigen receptor recognition of antigen-presenting molecules
… Unique TCR-pMHC-I complex structures Figure 2 T cell antigen receptor (TCR) footprint onto
pMHC-I. TCR footprints onto its specific pMHC-I; MHC-I is in white, and peptides are in gray…
pMHC-I. TCR footprints onto its specific pMHC-I; MHC-I is in white, and peptides are in gray…
The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity.
P Marrack, R Shimonkevitz, C Hannum… - The Journal of …, 1983 - rupress.org
… designed to bolster the idea that the T cell clone-specific antibodies described so far do
indeed bind to the Ag/MHC receptor on T cells. A clone-specific monoclonal antibody, KJ1-26.1, …
indeed bind to the Ag/MHC receptor on T cells. A clone-specific monoclonal antibody, KJ1-26.1, …
T-cell antigen receptor genes and T-cell recognition
MM Davis, PJ Bjorkman - Nature, 1988 - nature.com
… cells is the membrane-bound T-cell antigen receptor (TCR) which is specific for a combination
of foreign antigen … requirement of most B cells for “T cell help' in the form of specific growth/…
of foreign antigen … requirement of most B cells for “T cell help' in the form of specific growth/…
[PDF][PDF] The T cell antigen receptor: insights into organelle biology
RD Klausner, J Lippincott-Schwartz… - Annual review of cell …, 1990 - researchgate.net
… , and it is responsible for the ability of T cells to recognize and respond to specific antigens.
… Subunits of the T Cell Antigen Receptor Current data suggest that all T cell antigen receptors …
… Subunits of the T Cell Antigen Receptor Current data suggest that all T cell antigen receptors …
The B-cell antigen receptor complex: structure and signal transduction
CM Pleiman, D D'Ambrosio, JC Cambier - Immunology today, 1994 - cell.com
… during B-cell development n'12, support the contention that this receptor complex may
mediate the activation of B-cell maturation. The apparent non-antigen specificity of the receptor …
mediate the activation of B-cell maturation. The apparent non-antigen specificity of the receptor …
Selection of amino acid sequences in the beta chain of the T cell antigen receptor
SM Hedrick, I Engel, DL McElligott, PJ Fink, ML Hsu… - Science, 1988 - science.org
… The relation between the structure of the receptor and its functional specificity was … of the
receptors cxpressed by a series of T lymphocyte dones specific for a model antigen, pigeon …
receptors cxpressed by a series of T lymphocyte dones specific for a model antigen, pigeon …
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