Carcinogen-DNA adducts as a biomarker for cancer risk
A Rundle - … Research/Fundamental and Molecular Mechanisms of …, 2006 - Elsevier
… , the presence of carcinogen-DNA adducts in white blood cells, as measured by 32 P-…
The study by Benhamou and colleagues enrolled 120 cases with transitional cell carcinoma …
The study by Benhamou and colleagues enrolled 120 cases with transitional cell carcinoma …
In vitro Benzo[a]pyrene Diol Epoxide–Induced DNA Adducts and Risk of Squamous Cell Carcinoma of Head and Neck
D Li, LE Wang, P Chang, AK El-Naggar, EM Sturgis… - Cancer research, 2007 - AACR
… developed the in vitro carcinogen-induced adduct assay that can be measured under the …
DNA adduct levels in cultured peripheral lymphocytes and found that such induced adduct …
DNA adduct levels in cultured peripheral lymphocytes and found that such induced adduct …
DNA adducts in human carcinogenesis: etiological relevance and structure-activity relationship
H Bartsch - Mutation Research/Reviews in Genetic Toxicology, 1996 - Elsevier
… DNA adducts from (i) benzo[a]pyrene (BP), (ii) alkylation exposure, and (iii) etheno(e)-DNA
adduct-… and endogenous DNA damage, to examine the effect of drug polymorphism on BP …
adduct-… and endogenous DNA damage, to examine the effect of drug polymorphism on BP …
Prediction of treatment outcome by cisplatin‐DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin …
FJP Hoebers, D Pluim, M Verheij… - … journal of cancer, 2006 - Wiley Online Library
… patients with higher adduct levels (p = 0.06). In conclusion, cisplatin-DNA adduct formation
in … No differences were observed in intratumoral adduct levels between IA and IV treatments, …
in … No differences were observed in intratumoral adduct levels between IA and IV treatments, …
Correlation of DNA adduct levels with tumor incidence: carcinogenic potency of DNA adducts
M Otteneder, WK Lutz - Mutation Research/Fundamental and Molecular …, 1999 - Elsevier
… DNA adducts and tumor incidence is evaluated in this review. All available data on DNA
adduct … For the correlation with tumor incidence, the DNA adduct levels measured at the given …
adduct … For the correlation with tumor incidence, the DNA adduct levels measured at the given …
Distribution of DNA adducts caused by inhaled formaldehyde is consistent with induction of nasal carcinoma but not leukemia
K Lu, LB Collins, H Ru, E Bermudez… - Toxicological …, 2010 - academic.oup.com
… Nasal squamous cell carcinomas are rare in nonexposed rats but were very prominent in
rats exposed to 10- or 15-ppm formaldehyde. This improved understanding of the mechanisms …
rats exposed to 10- or 15-ppm formaldehyde. This improved understanding of the mechanisms …
Polycyclic aromatic hydrocarbon‐DNA adducts in liver tissues of hepatocellular carcinoma patients and controls
SY Chen, LY Wang, RM Lunn, WY Tsai… - … journal of cancer, 2002 - Wiley Online Library
… AFB 1 -DNA adducts and 4-ABP-DNA adducts were previously measured in these tissue …
AFB 1 -DNA adducts were categorized as positive or negative,20 while 4-ABP-DNA adducts …
AFB 1 -DNA adducts were categorized as positive or negative,20 while 4-ABP-DNA adducts …
Association between carcinogen-DNA adducts in white blood cells and lung cancer risk in the physicians health study
D Tang, DH Phillips, M Stampfer, LVA Mooney, Y Hsu… - Cancer research, 2001 - AACR
… , the nuclease P1 enhancement method has been shown to recover 93% of adducts (9). In
the present study, total DNA adduct levels were measured in the DRZ … Large cell carcinoma 8 …
the present study, total DNA adduct levels were measured in the DRZ … Large cell carcinoma 8 …
Evidence of differential cisplatin-DNA adduct formation, removal and tolerance of DNA damage in three human lung carcinoma cell lines
SA Shellard, AMJ Fichtinger-Schepman… - Anti-Cancer …, 1993 - journals.lww.com
… in two lung cancer cell lines, one derived from a small cell carcinoma (SW1271) and the
other from an adenocarcinoma (A549), relative to a drug-sensitive small cell line SW900, was …
other from an adenocarcinoma (A549), relative to a drug-sensitive small cell line SW900, was …
Mass spectrometry for the assessment of the occurrence and biological consequences of DNA adducts
… DNA adducts. In this review, we summarized the development of MS techniques on these
fronts for DNA adduct … for the quantitative measurement of DNA adducts, and the use of LC-MS …
fronts for DNA adduct … for the quantitative measurement of DNA adducts, and the use of LC-MS …