… , we should better understand the genetic background of these cells, especially the mutation
profile. Otherwise, it may affect the authenticity of experimental results. For example, TP53 …

Background Lung squamous cell carcinoma (LUSC) accounts for 20–30% of non-small cell
lung cancers (NSCLCs). There are limited treatment strategies for LUSC in part due to our …

… and squamous cell carcinoma in the Chinese NSCLC patients. This study emphasizes the
need for mutational profiling in all NSCLC patients to identify actionable mutations amenable …

… safety profile. Clinical trials of tazemetostat in patients with solid tumours bearing EZH2
gain-of-function mutations, including renal medullary carcinoma, are currently underway 81,82 . …

… We then used the “GenVisR” package to visualize the landscape of mutation profiles in …
mutation effect, and missense mutation was one of the most common mutation types in mutated …

Purpose: Sarcomatoid renal cell carcinoma (SRCC) ranks among the most aggressive
clinicopathologic phenotypes of RCC. However, the paucity of high-quality, genome-wide …

… The mutation profile of our current cohort of endometrial CCC is more serous-like than … with
serous carcinoma in its mutation profile, except in a subset of TP53-mutated endometrial CCC…

… the mutation profiles of a large series of endometrial carcinomas, … to improve the classification
of endometrial carcinomas. … A small number of clear cell carcinomas were specifically …

… cell carcinoma (HNSCC) originates from squamous cells and … We summarize 20 studies that
compared mutational profiles … varied greatly and the most mutated and the most concordant …

… -cell carcinomas as tumors that have a mutation profile that is … marker-null large-cell
carcinomas is further supported by our … BRAF mutations (combined rate 30%)—a mutation profile …