Toll‐like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas
C Rydberg, A Månsson, R Uddman, K Riesbeck… - …, 2009 - Wiley Online Library
… and certain TLR agonists appear to promote cell death in tumours. Imiquimod, a TLR7/8
agonist, is used clinically for treating basal cell carcinomas, and in the past TLR3 agonists have …
agonist, is used clinically for treating basal cell carcinomas, and in the past TLR3 agonists have …
Muscarinic receptor agonists and antagonists: effects on cancer
ER Spindel - Muscarinic receptors, 2012 - Springer
… cells such as pulmonary neuroendocrine cells that express muscarinic receptors can be …
might also inhibit growth of Merkel Cell Carcinomas, but this again needs to be determined. …
might also inhibit growth of Merkel Cell Carcinomas, but this again needs to be determined. …
Clinical investigations of Toll-like receptor agonists
T Meyer, E Stockfleth - Expert opinion on investigational drugs, 2008 - Taylor & Francis
… : Imiquimod was the first TLR agonist approved for treatment of anogenital warts, actinic
keratosis and superficial basal cell carcinoma in humans. Several other agonists of TLRs 4, 7, 8 …
keratosis and superficial basal cell carcinoma in humans. Several other agonists of TLRs 4, 7, 8 …
Death receptor agonists as a targeted therapy for cancer
J Wiezorek, P Holland, J Graves - Clinical cancer research, 2010 - AACR
… responses reported in phase 1 trials of the fully human DR5 agonist antibody conatumumab
[one patient with non–small cell lung carcinoma (NSCLC)] and dulanermin (one patient with …
[one patient with non–small cell lung carcinoma (NSCLC)] and dulanermin (one patient with …
Trial Watch: Toll-like receptor agonists for cancer therapy
E Vacchelli, A Eggermont, C Sautès-Fridman… - …, 2013 - Taylor & Francis
… keratosis, superficial basal cell carcinoma and external genital or perianal warts (condylomata
acuminata).Citation 57 Of note, while both BCG and MPL function as mixed TLR2/TLR4 …
acuminata).Citation 57 Of note, while both BCG and MPL function as mixed TLR2/TLR4 …
The use of Toll‐like receptor‐7 agonist in the treatment of basal cell carcinoma: an overview
E Stockfleth, U Trefzer, C Garcia‐Bartels… - British Journal of …, 2003 - academic.oup.com
… cell‐mediated immune response. Pre‐clinical studies have indicated the potential of this
TLR‐7 agonist … cell carcinoma syndrome (Gorlin–Goltz syndrome) has also been documented. …
TLR‐7 agonist … cell carcinoma syndrome (Gorlin–Goltz syndrome) has also been documented. …
To kill a tumor cell: the potential of proapoptotic receptor agonists
A Ashkenazi, RS Herbst - The Journal of clinical …, 2008 - Am Soc Clin Investig
… There is currently heightened interest in the extrinsic apoptosis pathway, with several
proapoptotic receptor agonists (PARAs) in development. The PARAs include the ligand …
proapoptotic receptor agonists (PARAs) in development. The PARAs include the ligand …
Targeting the transcription factor receptor LXR to treat clear cell renal cell carcinoma: agonist or inverse agonist?
G Wu, Q Wang, Y Xu, J Li, H Zhang, G Qi, Q Xia - Cell death & disease, 2019 - nature.com
… that both an LXR agonist and an XLR inverse agonist could inhibit proliferation and colony
formation and induce apoptosis in ccRCC cells. We observed that the LXR agonist LXR623 …
formation and induce apoptosis in ccRCC cells. We observed that the LXR agonist LXR623 …
Toll-like receptor agonists in cancer therapy
S Adams - Immunotherapy, 2009 - Taylor & Francis
… agonist) has been evaluated in several tumor types including renal cell carcinoma, glioblastoma,
melanoma, cutaneous T-cell … activity against basal cell carcinoma and melanoma in a …
melanoma, cutaneous T-cell … activity against basal cell carcinoma and melanoma in a …
Trial Watch: Experimental Toll-like receptor agonists for cancer therapy
L Galluzzi, E Vacchelli, A Eggermont… - …, 2012 - Taylor & Francis
… bladder carcinoma and the latter against actinic keratosis, superficial basal cell carcinoma,
… Salmonella minnesota that functions as a potent agonist or the TLR4-TICAM1 signaling axis,…
… Salmonella minnesota that functions as a potent agonist or the TLR4-TICAM1 signaling axis,…
相关搜索
- basal cell carcinoma receptor 7 agonist
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- treatment of facial basal cell carcinoma
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- oral and cutaneous squamous cell carcinomas