Challenges and directions in studying cellcell communication by extracellular vesicles

G van Niel, DRF Carter, A Clayton… - … Reviews Molecular Cell …, 2022 - nature.com
Extracellular vesicles (EVs) are membrane-bound particles released by cells into the extracellular
… of consensus regarding mechanisms of cellcell communication via EVs, as with any …

Extracellular vesicles as an emerging mechanism of cell-to-cell communication

C Tetta, E Ghigo, L Silengo, MC Deregibus, G Camussi - Endocrine, 2013 - Springer
… Since extracellular vesicles contain defined patterns of mRNA, microRNA, … cells. In this
review, we will discuss potential physiologic and pathological implications of extracellular vesicles

Focus on extracellular vesicles: new frontiers of cell-to-cell communication in cancer

C Ciardiello, L Cavallini, C Spinelli, J Yang… - International journal of …, 2016 - mdpi.com
… Today we know that cancer cells also communicate through EVs, thus transferring functional
information from cell to cell at the paracrine level (Figure 2). Recent reports are leading to …

Communication by extracellular vesicles: where we are and where we need to go

M Tkach, C Théry - Cell, 2016 - cell.com
Cells can communicate with neighboring cells or with distant cells through the secretion of
extracellular vesicles (EVs). … Cells can secrete different types of EVs that have been classified …

[HTML][HTML] Cell-to-cell communication by extracellular vesicles: focus on microglia

RC Paolicelli, G Bergamini, L Rajendran - Neuroscience, 2019 - Elsevier
… The inter-cellular communication via secreted extracellular vesicles has been solidly … of
the functional cargoes transferred from one cell to another in physiological and pathological …

[HTML][HTML] Role of lipid signalling in extracellular vesicles-mediated cell-to-cell communication

J Fyfe, I Casari, M Manfredi, M Falasca - Cytokine & Growth Factor Reviews, 2023 - Elsevier
cell-to-cell communication. In summary, lipid signalling is intricately involved in extracellular
vesicle-mediated cell-to-cell communication. … cells, and functional effects on recipient cells. …

Extracellular vesicles: novel mediators of cell communication in metabolic disease

I Huang-Doran, CY Zhang, A Vidal-Puig - Trends in Endocrinology & …, 2017 - cell.com
… (EVs; including exosomes) are circulating, cell-derived nanoparticles containing … cellular
targets. Accumulating evidence, reviewed herein, supports a role for extracellular vesicles in …

Extracellular vesicles as modulators of cell-to-cell communication in the healthy and diseased brain

DM Pegtel, L Peferoen, S Amor - … Transactions of the …, 2014 - royalsocietypublishing.org
… The role of extracellular vesicles in the healthy CNS. EVs carry signatures of the cell in …
The impact of such release depends upon the cell type releasing the EVs and the cell type …

Extracellular vesicles and cellcell communication in the cornea

JD Zieske, AEK Hutcheon, X Guo - The Anatomical Record, 2020 - Wiley Online Library
… One question that has intrigued cell biologists for many years is, “How do cells interact to …
discovery of extracellular vesicles (EVs) and the fact that they carry cargo, which directs cells to …

Emerging role of extracellular vesicles and cellular communication in metastasis

A Forder, CY Hsing, J Trejo Vazquez, C Garnis - Cells, 2021 - mdpi.com
… As a result, targeting the reciprocal communication between tumor cells and TME is a …
the EV-mediated cell-cell communication between tumor cells and various cells of the tumor …