Cell cycle regulation by p38 MAP kinases

C Ambrosino, AR Nebreda - Biology of the Cell, 2001 - Elsevier
… G1 progression during the cell cycle are not completely … revert pRb-mediated growth
suppression by inducing the … of the p38 MAP kinase pathway arrests cell cycle progression and …

MicroRNA 543 suppresses breast cancer cell proliferation, blocks cell cycle and induces cell apoptosis via direct targeting of ERK/MAPK

P Chen, W Xu, Y Luo, Y Zhang, Y He… - OncoTargets and …, 2017 - Taylor & Francis
… Furthermore, cell apoptosis and cell cycle were measured by … rate was upregulated when
cell lines were transfected with … regard to cell cycle ( Figure 2E ), it demonstrates that the cell

[HTML][HTML] MAPK inactivation is required for the G2 to M‐phase transition of the first mitotic cell cycle

A Abrieu, D Fisher, MN Simon, M Dorée… - The EMBO …, 1997 - embopress.org
… image Figure 1 Suppression of MAPK inactivation in Xenopus cell cycle extracts causes arrest
… We conclude that suppression of MAPK inactivation arrests cell cycle extracts at G 2 , but …

[HTML][HTML] Non-classical p38 map kinase functions: cell cycle checkpoints and survival

TM Thornton, M Rincon - International journal of biological …, 2009 - ncbi.nlm.nih.gov
… of p38 MAPK in the mediation of cell cycle checkpoints and cellMAPK regulates both the
G2/M as well as a G1/S cell cycle … While p38 MAPK has classically been associated with the …

The HBP1 transcriptional repressor and the p38 MAP kinase: unlikely partners in G1 regulation and tumor suppression

AS Yee, EK Paulson, MA McDevitt, K Rieger-Christ… - Gene, 2004 - Elsevier
cell cycle control and tumor suppression. Our objective is to review evidence for a new network
for cell cycle regulation involving both the p38 MAP kinase … tumor suppressive signaling …

Fangchinoline derivatives induce cell cycle arrest and apoptosis in human leukemia cell lines via suppression of the PI3K/AKT and MAPK signaling pathway

J Yang, S Hu, C Wang, J Song, C Chen, Y Fan… - European Journal of …, 2020 - Elsevier
… Indeed, variety of cell cycle regulators are … and MAPK/ERK pathways also causes cell cycle
arrest [23], we further assessed the effects of 3e on cell cycle progression, using HEL cells. …

Control of the eukaryotic cell cycle by MAP kinase signaling pathways

MG Wilkinson, JBA Millar - The FASEB Journal, 2000 - Wiley Online Library
… of cancer cells. Here we focus on the MAP kinase cascade and discuss the molecular
mechanisms by which these extensively studied signaling pathways influence cell growth and …

Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells

M Luo, Q Liu, M He, Z Yu, R Pi, M Li… - Journal of cellular …, 2017 - Wiley Online Library
… and LC3-II, while suppressed expression level of p62. Gartanin … in T98G cells is most likely
via cell cycle arrest modulated by … suppression of MMP-2/-9 activity which is involved in MAPK

Curcumin suppresses cardiac fibroblasts activities by regulating the proliferation and cell cycle via the inhibition of the p38 MAPK/ERK signaling pathway

G Fang, S Chen, Q Huang… - Molecular medicine …, 2018 - spandidos-publications.com
… In addition, it has been described that TGF-β1 activates the non-canonical MAPK pathway to
… of p38 MAPK and ERK. Thus, these findings indicated that curcumin suppressed p38 MAPK

[HTML][HTML] Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

SK Roy, RK Srivastava, S Shankar - Journal of molecular signaling, 2010 - Springer
… In addition to its role in regulating the PI3K/AKT cell survival pathway, PTEN also inhibits
growth factor-induced Shc phosphorylation and suppresses the MAP kinase signaling pathway […