Role of host cell secretory machinery in Zika virus life cycle
… virus co-circulates with Dengue viruses since cross-reactivity of Dengue and Zika virus
antibodies has been demonstrated in cell culture … against this emerging virus [15,16,17,18,19]. …
antibodies has been demonstrated in cell culture … against this emerging virus [15,16,17,18,19]. …
Zika virus infects human cortical neural progenitors and attenuates their growth
… Shown are sample flow cytometry analyses of distributions of hNPCs (from the C1-2 line)
at different phases of the cell cycle 72 hr after ZIKV or mock infection. For the mixture sample, …
at different phases of the cell cycle 72 hr after ZIKV or mock infection. For the mixture sample, …
[HTML][HTML] Genome-wide integrative analysis of Zika-virus-infected neuronal stem cells reveals roles for microRNAs in cell cycle and stemness
Zika virus (ZIKV) infection is implicated in severe fetal developmental disorders, including
microcephaly. MicroRNAs (miRNAs) post-transcriptionally regulate numerous processes …
microcephaly. MicroRNAs (miRNAs) post-transcriptionally regulate numerous processes …
[HTML][HTML] Zika virus envelope protein induces G2/M cell cycle arrest and apoptosis via an intrinsic cell death signaling pathway in neuroendocrine PC12 cells
J Liu, Q Li, X Li, Z Qiu, A Li, W Liang… - … Journal of Biological …, 2018 - ncbi.nlm.nih.gov
… PC12 cells. Our results confirmed the effect of ZIKV Env protein in interfering with the cell
cycle suggesting a role in abnormal nervous system development. The cell cycle arrest and …
cycle suggesting a role in abnormal nervous system development. The cell cycle arrest and …
Zika virus infection induces DNA damage response in human neural progenitors that enhances viral replication
C Hammack, SC Ogden, JC Madden Jr… - Journal of …, 2019 - Am Soc Microbiol
… cells (hNPCs) and leads to growth arrest of these cells, which … ZIKV, but not dengue virus,
disrupts the cell cycle of hNPCs by … ZIKV manipulates the cell cycle to benefit viral replication. …
disrupts the cell cycle of hNPCs by … ZIKV manipulates the cell cycle to benefit viral replication. …
Zika virus disrupts molecular fingerprinting of human neurospheres
PP Garcez, JM Nascimento, JM de Vasconcelos… - Scientific reports, 2017 - nature.com
… Interestingly, here we show that ZIKV alters cell cycle targets in progenitor cells, in parallel
to cell death induction. Our work provides insights into the molecular mechanisms behind …
to cell death induction. Our work provides insights into the molecular mechanisms behind …
Zika virus and the metabolism of neuronal cells
… Unlike DENV, Zika virus infects mature neuronal cells that express AXL receptors causing
neurological disorders [41]. Importantly, neurons lack the glycolysis promoting enzyme 6-…
neurological disorders [41]. Importantly, neurons lack the glycolysis promoting enzyme 6-…
Zika virus
D Musso, DJ Gubler - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) in the genus Flavivirus and the
family Flaviviridae . ZIKV was first isolated from a nonhuman primate in 1947 and from …
family Flaviviridae . ZIKV was first isolated from a nonhuman primate in 1947 and from …
Biology of Zika virus infection in human skin cells
R Hamel, O Dejarnac, S Wichit, P Ekchariyawat… - Journal of …, 2015 - Am Soc Microbiol
… Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family, which includes dengue,
West Nile, yellow fever, and Japanese encephalitis viruses… , and immature dendritic cells are …
West Nile, yellow fever, and Japanese encephalitis viruses… , and immature dendritic cells are …
Zika virus induced cellular remodelling
ED Rossignol, KN Peters, JH Connor… - Cellular …, 2017 - Wiley Online Library
… Zika virus (ZIKV) has been associated with morbidities such … The spread of this positive-sense,
single-stranded RNA virus … of the virus replication cycle within mammalian cells, we use …
single-stranded RNA virus … of the virus replication cycle within mammalian cells, we use …
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