Antioxidants, programmed cell death, and cancer

W Lopaczynski, SH Zeisel - Nutrition Research, 2001 - Elsevier
… mechanism for eliminating cancer cells, programmed cell death (also called apoptosis). …
form of cell death for their efficacy. In this review we present an overview of the role of ROS in …

Reactive oxygen species and programmed cell death

MD Jacobson - Trends in biochemical sciences, 1996 - cell.com
… These findings demonstrate that Bcl-2 and BcI-X L can inhibit PCD in the absence of ROS
and that, whatever antioxidant or ROSinhibiting properties Bcl-2 might have, they are not …

Reactive oxygen species (ROS) regulates different types of cell death by acting as a rheostat

GE Villalpando-Rodriguez… - … Medicine and Cellular …, 2021 - Wiley Online Library
… ; however, pretreatment with necrostatin-1 blocked TNF-α-induced cell death and
pretreatment with the antioxidant, butylated hydroxyanisole (BHA), blocked both induced …

Programmed cell-death by ferroptosis: antioxidants as mitigators

N Kajarabille, GO Latunde-Dada - International journal of molecular …, 2019 - mdpi.com
… Since ferroptosis is an iron-dependent and reactive oxygen species (ROS)-reliant cell death
that is induced by the glutathione-dependent antioxidant defenses, lipophilic antioxidants […

RNA viruses: ROS‐mediated cell death

ML Reshi, YC Su, JR Hong - International journal of cell …, 2014 - Wiley Online Library
… Studying the oxidative stress in HIV-infected patients has opened new doors for cellular ROS
researchers to use antioxidants as novel drugs to decrease HIV-1 pathogenesis in humans…

Reactive oxygen species as signals that modulate plant stress responses and programmed cell death

TS Gechev, F Van Breusegem, JM Stone, I Denev… - …, 2006 - Wiley Online Library
… redundant plant ROS network, composed of antioxidant enzymes, antioxidants and ROS-producing …
(44,54) Two well-described instances of ROS-induced programmed cell death in …

Remodelling of lace plant leaves: antioxidants and ROS are key regulators of programmed cell death

AN Dauphinee, JI Fletcher, GL Denbigh, CR Lacroix… - Planta, 2017 - Springer
… This study investigates the roles of antioxidants and ROS in developmental PCD signaling
… in the cell death gradient. This study investigated the role of antioxidants and ROS during …

[HTML][HTML] Vulnerability to ROS-induced cell death in ageing articular cartilage: the role of antioxidant enzyme activity

N Jallali, H Ridha, C Thrasivoulou, C Underwood… - Osteoarthritis and …, 2005 - Elsevier
cell death, as supported by our results showing increased vulnerability with age to
menadione-induced cell death… numbers and an increase in cellular ROS levels in rat articular …

Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants

B Poljsak, D Šuput, I Milisav - Oxidative medicine and cellular …, 2013 - Wiley Online Library
… Excessive reactive oxygen species (ROS) formation can induce oxidative stress, leading
to cell damage that can culminate in cell death. Therefore, cells have antioxidant networks to …

Mitochondrial reactive oxygen species in cell death signaling

C Fleury, B Mignotte, JL Vayssière - Biochimie, 2002 - Elsevier
… to cell death signaling. The present review will focus on the role of mitochondrial ROS in
cell death … 1) The addition of ROS or the depletion of endogenous antioxidants can promote …