… Further research into the regulation of GSDME expression and activation will elucidate
the complex circuitry underlying its cross talk among multiple cell death pathways. …

… contents inducting an inflammatory response and causing toxicity to adjacent healthy
cells leading to further cell death. This cell death mechanism may not be the best for cancer …

… cell deaths that occur in the nematode Caenorhabditis elegans, we first describe below what
is known about cell death … regulation of cell death is altered as T-cells mature. Programmed …

… cell death programme. Recently defined genetic connections between C. elegans cell death
… value of this system as a model for cell death in mammalian cells, which, inevitably, is more …

… Here we discuss the mechanisms underlying mitochondrial … evade cell death post-MOMP,
cells must limit caspase activation. Here we review mechanisms of caspase activity regulation …

… basic components of the cell death machinery. Activation and regulation of apoptosis in higher
… suppressor mechanism aimed at ensuring induction of cell death in response to improper …

… Nonetheless, studies from a variety of systems have permitted certain conclusions regarding
the regulation and nature of cell death in development. We shall review briefly evidence …

… cell death, recent work has revealed that these organelles also play an important role in the
regulation of apoptotic cell death by mechanisms … of these organelles in cell life and death. …

… -5 can lead to apoptosis rather than autophagic cell death 24. Thus, investigation of the
molecular mechanisms regulating various types of cell death and their crosstalk is vital, as they …

… In our opinion, perhaps the most important cell death event generated at the mitochondrial
level is the release of cytochrome c from the mitochondrial intermembrane space to the cytosol…