Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death

JJ Lemasters, T Qian, CA Bradham, DA Brenner… - Journal of bioenergetics …, 1999 - Springer
… reticulum, and moderate mitochondrial swelling accompany this bleb formation. … mitochondrial
dysfunction in cytotoxicity leading to necrotic cell death can be assessed To this point, cell

Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease

A Eckert, U Keil, CA Marques, A Bonert, C Frey… - Biochemical …, 2003 - Elsevier
mitochondrial dysfunction. Moreover, numerous lines of findings indicate increased susceptibility
to apoptotic cell deathmitochondrial dysfunction, caspase pathway, and neuronal loss. …

Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stress

M Akbar, MM Essa, G Daradkeh, MA Abdelmegeed… - Brain research, 2016 - Elsevier
… In fact, impaired mitochondrial function is commonly observed in … Mitochondrial dysfunction
under many pathological … (PTMs) of mitochondrial proteins and/or oxidative damage to …

Mitochondrial dysfunction and oxidative stress as determinants of cell death/survival in stroke

PH Chan - Annals of the New York Academy of Sciences, 2005 - Wiley Online Library
MITOCHONDRIA-DEPENDENT PATHWAY OF APOPTOSIS The cell death signaling pathway
in mitochondria … the ischemic brain with the release of mitochondrial cytochrome c, a water-…

[HTML][HTML] The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death

L Kamalian, AE Chadwick, M Bayliss, NS French… - Toxicology in vitro, 2015 - Elsevier
… , in which mitochondrial toxicity has been … for mitochondrial toxicity in new chemical entities
and models which can be used to link the onset of mitochondrial dysfunction with cell death

Mitochondrial clustering induced by overexpression of the mitochondrial fusion protein Mfn2 causes mitochondrial dysfunction and cell death

P Huang, T Yu, Y Yoon - European journal of cell biology, 2007 - Elsevier
… whether the cell death that we observed is apoptotic, we incubated cells in … the death of cells
containing clustered mitochondria. The proportion of cells containing clustered mitochondria

[HTML][HTML] Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death

MY Cha, SH Han, SM Son, HS Hong, YJ Choi, J Byun… - PloS one, 2012 - journals.plos.org
… measurements from mitochondrial functions to verify that the sole mitochondria-specific …
mechanism to cause the mitochondrial dysfunction that leads to cellular toxicity and death. …

[PDF][PDF] Mitochondrial dysfunction and oxidative stress in seizure-induced neuronal cell death

YC Chuang - Acta Neurol Taiwan, 2010 - ant-tnsjournal.com
cell death and subsequent epileptogenesis(13). This article will focus on the potential …
of mitochondrial dysfunction and oxidative stress in seizure-associated apoptotic cell death

[HTML][HTML] Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells

LAM Carneiro, LH Travassos, F Soares, I Tattoli… - Cell host & …, 2009 - cell.com
… induces a caspase-independent necrotic type of cell death associated with mitochondrial
dysfunction and that Nod1 plays a crucial role in the protection against this type of cell death. …

Bnip3 mediates mitochondrial dysfunction and cell death through Bax and Bak

DA Kubli, JE Ycaza, ÅB Gustafsson - Biochemical Journal, 2007 - portlandpress.com
… for Bnip3-mediated mitochondrial dysfunction and cell death. However, Bnip3 has been
reported to induce both caspase-dependent and -independent cell death. Although activation of …