Neuronal cell death mechanisms in major neurodegenerative diseases
… cell death and describe evidence for cell death in the context of individual common
neurodegenerative diseases, discussing our current understanding of cell death by connecting with …
neurodegenerative diseases, discussing our current understanding of cell death by connecting with …
Cell death: protein misfolding and neurodegenerative diseases
T Nakamura, SA Lipton - Apoptosis, 2009 - Springer
… Many neurodegenerative diseases are characterized by the accumulation of misfolded
proteins that adversely affect neuronal connectivity and plasticity, and trigger cell death signaling …
proteins that adversely affect neuronal connectivity and plasticity, and trigger cell death signaling …
Targeting programmed cell death in neurodegenerative diseases
M Vila, S Przedborski - Nature Reviews Neuroscience, 2003 - nature.com
… activation of PCD in neurodegenerative diseases is not a primary event. Instead, we think
it is a 'suicide' decision, taken by cells that are affected by disease-related abnormalities such …
it is a 'suicide' decision, taken by cells that are affected by disease-related abnormalities such …
[HTML][HTML] Mitochondrial and cell death mechanisms in neurodegenerative diseases
LJ Martin - Pharmaceuticals, 2010 - mdpi.com
… cell death to three human neurodegenerative diseases (Alzheimer’s disease, Parkinson’s
disease… for mitochondrial involvement, and their animal and cell models. In this regard varying …
disease… for mitochondrial involvement, and their animal and cell models. In this regard varying …
Cell death mechanisms of neurodegeneration
… cell death found in neurodegenerative diseases are summarized in Table 16.1 (adapted from
[3, 14, 17]). It is worth noting that the cell may favor one form of death … of the cell. Thus, only …
[3, 14, 17]). It is worth noting that the cell may favor one form of death … of the cell. Thus, only …
Mechanisms of cell death in neurodegenerative diseases: fashion, fiction, and facts
MB Graeber, LB Moran - Brain pathology, 2002 - Wiley Online Library
… of neuronal cell death mechanisms. In addition, a non-neurodegenerative condition, ischemia,
… Glio-degenerative diseases, such as multiple system atrophy or cell death following direct …
… Glio-degenerative diseases, such as multiple system atrophy or cell death following direct …
Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling
AM Gorman - Journal of cellular and molecular medicine, 2008 - Wiley Online Library
… cell death in neurodegenerative diseases. The underlying genetic basis of some
neurodegenerative diseases … cell death in these diseases and the type of cell death that is …
neurodegenerative diseases … cell death in these diseases and the type of cell death that is …
Molecular mechanisms of cell death in neurological diseases
… cell death processes and the roles they play in contributing to neurodegenerative diseases
or … We also discuss the interplay between distinct cell death signalling cascades and disease …
or … We also discuss the interplay between distinct cell death signalling cascades and disease …
Apoptosis and caspases in neurodegenerative diseases
RM Friedlander - New England Journal of Medicine, 2003 - Mass Medical Soc
… Chronic Neurodegenerative Diseases Cell death in chronic neurodegenerative diseases
often occurs as a result of a mutation in one or several genes. This genetic alteration changes …
often occurs as a result of a mutation in one or several genes. This genetic alteration changes …
The therapeutic importance of understanding mechanisms of neuronal cell death in neurodegenerative disease
TE Golde - Molecular neurodegeneration, 2009 - Springer
Despite major advances in our understanding of the initiating factors that trigger many
neurodegenerative disorders, to date, no novel disease-modifying therapies have been shown to …
neurodegenerative disorders, to date, no novel disease-modifying therapies have been shown to …
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