Nitric oxide (NO) has several essential roles in mammals, but unregulated NO production
can cause cell death … Such disturbances can lead to either apoptotic or necrotic cell death, …

… of NO in cell signalling, synaptic transmission, and cell death. We focus also on the protective
role as well as the toxicity of NO. Finally, the adverse effects of inhaled nitric oxide are also …

… This review discusses the mechanisms by which NO induces cell death, in particular, the
role of mitochondria in NO-induced apoptosis and necrosis. It also brie y outlines NO …

… to either chemical donors of nitric oxide or to inducers of the nitric oxide synthase. In this …
the cytotoxicity of nitric oxide and discuss possible mechanisms that may lead to cell death. …

… (l-NMMA), a nitric oxide-synthase (NOS; EC 1.14.13.39) inhibitor. Our results show that nitric
oxide leads to irreversible DNA fragmentation and cell death under stressful conditions, and …

… by different capacities of cells to cope with the … , cell death and cell survival. These NO-mediated
actions will contribute to a better understanding of the impact of inducible nitric oxide …

… Low levels of NO can block cell death via cGMP-mediated: vasodilation, Akt activation or
block of mitochondrial permeability transition. High NO may protect by killing pathogens, …

… Nitric oxide (NO) and its derivatives (reactive nitrogen species, RNS) inhibit mitochondrial
respiration and either stimulate or inhibit cell death depending on conditions. This review …

… Nitric oxide (NO) activates the intrinsic apoptotic pathway to induce cell death. However, the
mechanism by which this pathway is activated in cells exposed to NO is not known. Here we …

… cell death have been invoked as the mechanism underlying progressive cardiomyocyte
dropout. Nitric oxide (… not only cardiac function, but also cell death elicited by both apoptotic and …