Impact of Phosphorylcholine Expression on the Adherence and Invasion of Streptococcus pyogenes to Epithelial Cells

H Iuchi, J Ohori, H Matsuzaki, T Tokushige, S Toge… - Microorganisms, 2022 - mdpi.com
cells is often associated with high levels of cell death, and S. pyogenes induce apoptosis in
infected human epithelial cells [4]. … , and cells involved in the regulation of anti-PC antibody

Phosphocholine as a pattern recognition ligand for CD361

A Boullier, P Friedman, R Harkewicz, K Hartvigsen… - Journal of lipid …, 2005 - ASBMB
phosphocholine (POVPC). The current study was designed to examine whether the
phosphocholine … determined by flow cytometry using the anti-human CD36 antibody, clone …

… CELLULAR MECHANISMS OF THE POLYSLONAL ANTIBODY RESPONSE; INDUCTION OF POLYCLONAL ANTIBODY SECRETION BY PHOSPHORYLCHOLINE.

E Beckman - 1984 - search.proquest.com
… and in the lipid bilayers of mammalian cells (13). The possible importance of phosphorylcholine
as a regulator of polyclonal antibody responses towards bacteria and its possible …

Cytotoxic phospholipid oxidation products: cell death from mitochondrial damage and the intrinsic caspase cascade

R Chen, L Yang, TM McIntyre - Journal of Biological Chemistry, 2007 - ASBMB
… cation [M+H + ]of m/z 652 producing a phosphocholine daughter ion of m/z 184. The average
of … monoclonal antibodies. Each panel is representative of three independent experiments. …

Cross-reactivity of anti-phosphorylcholine antibodies to neuromuscular blockers in a murine model of immunization

RM Mazzuco, MN Sato… - International …, 2007 - Elsevier
… production of antibodies directed to phosphorylcholine analogs, … of anti-phosphorylcholine
(PC) antibodies between males … The isotype profile of the antibodies and their cross-reactivity …

Oxidized phosphatidylcholine formation and action in oligodendrocytes

J Qin, FD Testai, S Dawson, J Kilkus… - Journal of …, 2009 - Wiley Online Library
… (POVPC)] is specifically recognized by both the B-1 cell natural antibody T15… -phosphorylcholine
was able to activate NSMase and cause cell death in other cell lines such as a HOG cell

Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease

CA Gleissner, C Erbel, J Haeussler… - Clinical Research in …, 2015 - Springer
… Low anti-phosphorylcholine (PC) IgM plasma levels have been associated with increased …
We hypothesized that atheroprotection mediated by anti-PC IgM antibodies is associated with …

Platelet-activating factor receptor initiates contact of Acinetobacter baumannii expressing phosphorylcholine with host cells

Y Smani, F Docobo-Pérez, R López-Rojas… - Journal of Biological …, 2012 - ASBMB
… baumannii and the host cells remains unclear. Here, we demonstrated that the
phosphorylcholine (ChoP)-containing outer membrane protein of A. baumannii binds to A549 cells

Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men

B Gigante, K Leander, M Vikström, D Baldassarre… - Atherosclerosis, 2014 - Elsevier
Objective Low levels of IgM anti-phosphorylcholine (anti-PC) increase the risk of cardiovascular
events (CVE). Here we investigate the association of low anti-PC with the progression of …

[HTML][HTML] Targeting Phosphorylcholine in Established Atherosclerosis?

D Tsiantoulas - Basic to Translational Science, 2020 - jacc.org
… Therapeutic antibody against phosphorylcholine preserves coronary function and attenuates
Vascular 18 F-FDG uptake in atherosclerotic mice". J Am Coll Cardiol Basic Trans Science …