Death‐associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death

Y Lin, TR Hupp, C Stevens - The FEBS journal, 2010 - Wiley Online Library
… (DAPK) is a stress-regulated protein kinase that mediates a range of processes, including
signal-induced cell death and autophagy. Although the kinase domain of DAPK has a range of …

Protein kinase Cε makes the life and death decision

A Basu, U Sivaprasad - Cellular signalling, 2007 - Elsevier
… in turn leads to cleavage of critical cellular proteins, resulting in cell death. While caspase-8,
-… There are two major pathways of cell death. The extrinsic pathway is triggered by binding of …

Death‐associated protein kinase (DAPK) and signal transduction: blebbing in programmed cell death

M Bovellan, M Fritzsche, C Stevens… - The FEBS …, 2010 - Wiley Online Library
… In contrast, in DAPK-mediated cell death, blebbing is independent from Rho kinases or the
… and Ser19 by DAPK family proteins, such as DAPK and zipper (ZIP) kinase. In the case of …

Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions

G Shani, L Marash, D Gozuacik, S Bialik… - … and cellular biology, 2004 - Taylor & Francis
… To further investigate the basis for the strong functional interaction between the two
protein kinases, we tested whether they physically interact with each other by using …

[HTML][HTML] DAP‐kinase is a Ca2+/calmodulin‐dependent, cytoskeletal‐associated protein kinase, with cell death‐inducing functions that depend on its catalytic activity

O Cohen, E Feinstein, A Kimchi - The EMBO journal, 1997 - embopress.org
… ‐kinase was initially identified as a gene whose anti‐sense‐mediated reduced expression
protected HeLa cells from interferon‐γ‐induced programmed cell death. … 160 kDa protein was …

US3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with programmed cell death protein 4 (PDCD4) to block apoptosis

X Wang, C Patenode… - Proceedings of the …, 2011 - National Acad Sciences
… The U S 3 protein kinase is similar to protein kinasecell death protein 4 (PDCD4). We report
that U S 3 interacts with PDCD4, that PDCD4 is posttranslationally modified in infected cells

The dsRNA-dependent protein kinase, PKR and cell death.

GN Barber - Cell Death & Differentiation, 2005 - nature.com
… infection and other forms of cellular stress. Here, we discuss some of the properties of PKR
including its role as an accessory of cell death. Virus infection of the cell leads to activation of …

The death-associated protein kinases: structure, function, and beyond

S Bialik, A Kimchi - Annu. Rev. Biochem., 2006 - annualreviews.org
… functions and is linked to several cell death–related signaling pathways. Furthermore, it is …
of closely related kinases, all of which have been associated with cell death. The purposes of …

Two faces of protein kinase Cδ: the contrasting roles of PKCδ in cell survival and cell death

A Basu, D Pal - The scientific world journal, 2010 - Wiley Online Library
Protein kinase Cδ (PKCδ) is a member of the PKC family that plays a critical role in the regulation
of various cellular processes, including cell proliferation, cell death… proapoptotic protein

How protein kinase C activation protects nerve cells from oxidative stress-induced cell death

P Maher - Journal of Neuroscience, 2001 - Soc Neuroscience
… oxidative stress-induced cell death mediated by protein kinase C activation is attributable
to the modulation of the activities of multiple members of the MAPK kinase family. However, …