… Furthermore, DJ-1 was sumoylated through binding to the SUMO-1 ligase PIAS that … Here,
we examined the effect of down regulation or over-expression of DJ-1 on the cell death after …

… The aim of this study was to determine the role of DJ‐1 in PD. We first found that DJ‐1
eliminated hydrogen peroxide in vitro by oxidizing itself. We then found that DJ‐1 knockdown by …

… DJ-1 has a favorable role in maintaining these neurons. Here, we show that DJ-1 protects
against oxidative stress-induced cell death, … Third, DJ-1 has been recognized as a regulatory …

… DJ-1 deficiency ameliorates death in the context of acute ER stress in vitro and in vivo. DJ-1 …
and mutant DJ-1 in the regulation of UPR and provides a potential link to PD pathogenesis. …

… report that DJ-1 protects against UV-induced cell death through the … that MEKK1 is the direct
target of DJ-1. The C-terminus of … ability of DJ-1 is not sufficient to regulate oxidative stress-…

… DJ-1 was found to play a role in transcriptional regulation: a positive regulator of the
androgen receptor Citation[10-12] and p53 [Citation[13]] and a negative regulator of PTEN tumor …

… -regulation of DJ-1 … cell death mediated by DJ-1 deficiency, we co-injected DJ-1 MOs with
MOs either directed against p53 or its negative regulator mdm2. At 3 dpf, co-injection of DJ-1/…

… regulates expression of several genes during oxidative stress, we also hypothesized that
ROS may regulate the nuclear translocation of DJ-1. Previously, our laboratory showed that …

… physiological and pathological role of DJ-1, a Parkinson’s … DJ-1, from which its ability to
modulate signaling pathways seems to be of utmost importance for cell death regulation by DJ-1. …

… Capturing of extracellular DJ-1 by using anti-DJ-1 antibody had reduced both cell viability
and mitochondrial activity, whereas intracellular glutathione (GSH) levels, a marker of …